Predictive ability of prognostic nutritional index in surgically resected gastrointestinal stromal tumors: a propensity score matching analysis
Predictive ability of prognostic nutritional index in surgically resected gastrointestinal stromal tumors: a propensity score matching analysis
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手术切除胃肠道间质瘤预后营养指数的预测能力：倾向评分匹配分析
DOI：
10.1093/jjco/hyz078
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发表时间：
2019-09-01
影响因子：
2.4
通讯作者：
Wei, Zhe-Wei
中科院分区：
文献类型：
--
作者：
Shi, Wei-Kun;Zhang, Xin-Hua;Wei, Zhe-Wei
背景：最近的研究表明，炎症指数与各种恶性肿瘤的预后有关。然而，包括血小板与淋巴细胞比值、中性粒细胞与淋巴细胞比值和预后营养指数在内的炎症指标对胃肠道间质瘤（gist）的有用性仍存在争议。方法：回顾性分析2005 - 2015年间接受手术切除的340例原发性局限性GIST患者，探讨血小板与淋巴细胞比值、中性粒细胞与淋巴细胞比值及预后营养指数对预后的影响。采用倾向评分匹配法选择206例患者，以控制选择偏差。结果：Kaplan-Meier分析和log rank检验显示，高预后营养指数（>= 43.9）与较好的无复发生存期（RFS）显著相关(P
Background: Recent findings have shown that inflammation indices are associated with prognosis in various malignancies. However, the usefulness of inflammation indices including platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio and prognostic nutritional index for gastrointestinal stromal tumors (GISTs) remains controversial.Methods: We retrospectively reviewed 340 primary localized GIST patients who had received surgical resection between 2005 and 2015 to investigate the effect of platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio and prognostic nutritional index on prognosis. 206 patients were selected by propensity score matching to control selection biases.Results: Kaplan-Meier analysis and the log rank test demonstrated that high prognostic nutritional index (>= 43.9) was significantly correlated with better recurrence-free survival (RFS) (P