Cystic versus predominantly cystic thyroid nodules: efficacy of ethanol ablation and analysis of related factors
Cystic versus predominantly cystic thyroid nodules: efficacy of ethanol ablation and analysis of related factors
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DOI：
10.1007/s00330-012-2406-5
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发表时间：
2012-07-01
影响因子：
5.9
通讯作者：
Shong, Young Kee
中科院分区：
文献类型：
--
作者：
Kim, Young Joong;Baek, Jung Hwan;Shong, Young Kee
比较无水乙醇消融（EA）治疗囊性和囊性为主甲状腺结节的疗效，并评价影响疗效的因素。在EA前后评估患者的疼痛体积、症状和美容评分。比较电针治疗囊性结节和以囊性为主结节的疗效;对每种类型的疗效进行了评估，包括初始体积、固体成分、血管分布、液体性质、乙醇保留时间和EA次数，平均结节体积从15.7 ± 18.1 ml减少到3.0 ± 7.9 ml（平均减容率，85.2 ± 16.1%），治疗成功率为90.3%。EA对囊性结节的疗效明显高于以囊性为主的结节。所有结节的EA疗效的独立预测因素包括初始体积、实体成分和血管分布。初始体积和血管分布是主要囊性结节EA疗效的独立预测因素，但没有因素与囊性结节的疗效独立相关。EA在大的或血管为主的囊性结节中效果较差，但无论相关因素如何，在囊性结节中有效。超声引导下的乙醇消融越来越多地用于囊性甲状腺结节。EA似乎对囊性和以囊性为主的结节有效，尤其是囊性结节。
To compare the efficacy of ethanol ablation (EA) of cystic and predominantly cystic thyroid nodules, and to evaluate factors affecting efficacy.From October 2008 to December 2010, a total of 217 thyroid nodules were treated with EA. Nodule volumes, symptoms and cosmetic scores were evaluated before and after EA. EA efficacy in treating cystic and predominantly cystic nodules was compared; and factors related to EA efficacy in each type, including initial volume, solid component, vascularity, fluid nature, ethanol retention time and number of EA sessions, were evaluated.Mean nodule volume decreased from 15.7 +/- 18.1 ml to 3.0 +/- 7.9 ml (mean volume reduction, 85.2 +/- 16.1%) and the therapeutic success rate was 90.3% at last follow-up. EA was significantly more effective in cystic than predominantly cystic nodules. Independent predictors of EA efficacy for all nodules included initial volume, solid component and vascularity. Initial volume and vascularity were independent predictors of EA efficacy in predominantly cystic nodules, but no factor was independently related to efficacy in cystic nodules.EA is effective in both cystic and predominantly cystic nodules, especially the former. EA is less effective in large or vascular predominantly cystic nodules, but is effective in cystic nodules regardless of related factors.aEuro cent Ethanol ablation under ultrasound guidance is increasingly used for cystic thyroid nodules.aEuro cent EA seems effective for cystic and predominantly cystic nodules, especially cystic nodules.aEuro cent The effectiveness of EA was reduced in large or vascular predominantly cystic nodules.