SMOKING AND ULCERATIVE-COLITIS
SMOKING AND ULCERATIVE-COLITIS
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DOI：
10.1136/bmj.288.6419.751
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发表时间：
1984-01-01
影响因子：
105.7
通讯作者：
LANGMAN, MJS
中科院分区：
文献类型：
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作者：
LOGAN, RFA;EDMOND, M;LANGMAN, MJS
在一项针对吸烟和溃疡性结肠炎的病例对照研究中，与年龄和性别相匹配的社区对照相比，患有该疾病的患者吸烟的可能性较小。差异很大，不吸烟或当前习惯的估计相对风险为 3.8，当检查疾病发作时的习惯时，该差异甚至更大 (6.2)，主要是由于 55 名患者中的 42 名在发病前平均戒烟 8 年。这种关联不能用社会阶层的混杂来解释。这些发现表明吸烟直接或间接地可以预防溃疡性结肠炎。
In a case-control study of smoking and ulcerative colitis patients with the disease were less likely to smoke than community controls matched for age and sex. The difference was substantial, with an estimated relative risk of 3.8 for nonsmoking or current habits, was even larger (6.2) when habits at onset of the disease were examined and was mainly accounted for by 42 of 55 patients who had given up smoking a mean of 8 yr before onset. The association could not be explained by confounding by social class. These findings suggested that smoking directly or indirectly confered protection against ulcerative colitis.