Development of Short-Form Versions of the Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R): A Proof-of-Principle Study.

Development of Short-Form Versions of the Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R): A Proof-of-Principle Study.
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疼痛患者筛选器和阿片类药物评估修订版 (SOAPP-R) 的简短版本的开发:一项原理验证研究。

DOI:
10.1093/pm/pnw210
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发表时间:
2017
期刊:
Pain medicine (Malden, Mass.)
影响因子:
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通讯作者:
Butler,StephenF
Butler,StephenF
中科院分区:
--
文献类型:
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作者:
Finkelman,MatthewD;Smits,Niels;Kulich,RonaldJ;Zacharoff,KevinL;Magnuson,BrittaE;Chang,Hong;Dong,Jinghui;Butler,StephenF

文献摘要

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背景。The screening and Opioid Assessment for Patients with pain - revised (soap -r)是一份24项问卷,旨在评估慢性疼痛患者异常药物相关行为的风险。目的:开发和评价候选的SOAPP-R短表。设计。回顾性研究。设置。疼痛中心。受试者。428例慢性非癌性疼痛患者。方法:受试者先前使用完整版SOAPP-R,并通过异常药物行为量表对异常药物相关行为进行阳性或阴性分类指数(ADBI)。soap - r的简短形式是使用套索逻辑回归开发的。使用完整的数据集、训练测试分析和10倍交叉验证,计算所有形式ADBI的敏感性、特异性和曲线下面积(AUC)。并计算了每种形式的alpha系数。结果:在完整的数据集分析中,包含12个项目的表格显示出敏感性、特异性和AUC大于或等于全长soap - r(分别为0.74、0.67和0.76)。简式的alpha系数为0.76。在训练检验分析和10倍交叉验证中,其AUC值与全长soap - r的AUC值在0.01以内。结论:soap - r的12项版本有潜力作为一个简短的风险筛选器,应该进行前瞻性的测试。
Background.The Screener and Opioid Assessment for Patients with Pain–Revised (SOAPP-R) is a 24-item questionnaire designed to assess risk of aberrant medication-related behaviors in chronic pain patients. The introduction of short forms of the SOAPP-R may save time and increase utilization by practitioners.Objective.To develop and evaluate candidate SOAPP-R short forms.Design.Retrospective study.Setting.Pain centers.Subjects.Four hundred and twenty-eight patients with chronic noncancer pain.Methods.Subjects had previously been administered the full-length version of the SOAPP-R and been categorized as positive or negative for aberrant medication-related behaviors via the Aberrant Drug Behavior Index (ADBI). Short forms of the SOAPP-R were developed using lasso logistic regression. Sensitivity, specificity, and area under the curve (AUC) of all forms were calculated with respect to the ADBI using the complete data set, training-test analysis, and 10-fold cross-validation. The coefficient alpha of each form was also calculated. An external set of 12 pain practitioners reviewed the forms for content.Results.In the complete data set analysis, a form of 12 items exhibited sensitivity, specificity, and AUC greater than or equal to those of the full-length SOAPP-R (which were 0.74, 0.67, and 0.76, respectively). The short form had a coefficient alpha of 0.76. In the training-test analysis and 10-fold cross-validation, it exhibited an AUC value within 0.01 of that of the full-length SOAPP-R. The majority of external practitioners reported a preference for this short form.Conclusions.The 12-item version of the SOAPP-R has potential as a short risk screener and should be tested prospectively.