Growth deficits in ADHD children revisited: evidence for disorder-associated growth delays?

Growth deficits in ADHD children revisited: evidence for disorder-associated growth delays?
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重新审视多动症儿童的生长缺陷:与疾病相关的生长迟缓的证据?

DOI:
10.1097/00004583-199611000-00014
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发表时间:
1996
期刊:
Journal of the American Academy of Child and Adolescent Psychiatry.
影响因子:
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通讯作者:
Wilens,TE
Wilens,TE
中科院分区:
--
文献类型:
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作者:
Spencer,TJ;Biederman,J;Harding,M;O'Donnell,D;Faraone,SV;Wilens,TE

文献摘要

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目的重新评估兴奋剂导致注意缺陷多动障碍(ADHD)儿童生长缺陷的假说。方法对124例ADHD儿童和109名对照儿童进行身高和体重的生长缺陷检查,采用适当的年龄和父母身高校正措施,并关注青春期阶段、治疗和精神障碍的问题。结果ADHD儿童和对照组的身高差异很小。然而,身高缺陷在青春期早期但不是晚期ADHD儿童中很明显,并且与精神药物的使用无关。没有证据表明ADHD儿童与对照组相比体重不足,也没有发现营养不良指标与矮小之间的关系。结论SADHD可能与青春期中期的暂时性身高发育障碍有关,这种发育障碍可能在青春期后期恢复正常。这种效应似乎是由ADHD介导的,而不是它的治疗。
OBJECTIVETo reevaluate the hypothesis that stimulants cause growth deficits in children with attention-deficit hyperactivity disorder (ADHD).METHODGrowth deficits in height and weight were examined in 124 children and adolescents with ADHD and 109 controls, using appropriate correction by age and parental height measures and attending to issues of pubertal stage, treatment, and psychiatric comorbidity.RESULTSSmall but significant differences in height were identified between ADHD children and controls. However, height deficits were evident in early but not late adolescent ADHD children and were unrelated to use of psychotropic medications. There was no evidence of weight deficits in ADHD children relative to controls, and no relationship between measures of malnutrition and short stature was identified.CONCLUSIONSADHD may be associated with temporary deficits in growth in height through mid-adolescence that may normalize by late adolescence. This effect appears to be mediated by ADHD and not its treatment.