Associations of sleep quality with incident atrial fibrillation: a meta-analysis
Associations of sleep quality with incident atrial fibrillation: a meta-analysis
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DOI：
10.1111/imj.13764
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发表时间：
2018-08-01
影响因子：
2.1
通讯作者：
Cheungpasitporn, Wisit
中科院分区：
文献类型：
--
作者：
Chokesuwattanaskul, Ronpichai;Thongprayoon, Charat;Cheungpasitporn, Wisit
背景：睡眠呼吸暂停与心房颤动（AF）之间的密切关系是众所周知的。然而，目前尚不清楚是否睡眠质量与AF.Aim相关：为了评估睡眠持续时间，失眠和频繁觉醒与AF.Methods的关联：在MEDLINE，EMBASE，科克伦数据库中进行了系统回顾，从一开始到2017年9月，以确定研究，评估AF的风险，在成人短睡眠时间，长睡眠时间，失眠和/或频繁觉醒。从个别研究的效果估计提取和合并使用随机效应，通用的逆方差方法DerSimonian和Laird.Results：10个观察性研究（14 296 314例患者）。睡眠时间短（< 6 h）和睡眠时间长（> 8 h）的个体发生AF的合并比值比（OR）分别为1.20（95%置信区间（CI）0.93-1.55，I-2 = 66%）和1.24（95% CI 0.96-1.62，I-2 = 58%）。睡眠时间增加与房颤之间无关联，合并OR为0.97（95%CI 0.84-1.12，I-2 = 0%）。然而，AF与失眠和频繁觉醒有显著相关性，合并OR为1.30（95% CI 1.26-1.35，I-2 = 3%）和1.36（95% CI 1.13-1.63，I-2 = 55%）。我们的研究结果表明，AF和睡眠时间之间没有关联，但揭示了AF与失眠和频繁夜间觉醒之间的潜在关联。因此，需要进一步研究房颤与睡眠质量的关系。
Background: The strong relationship between sleep apnoea and atrial fibrillation (AF) is well known. However, it remains unclear whether the sleep quality is related with AF.Aim: To evaluate the associations of sleep duration, insomnia and frequent awakening with AF.Methods: A systematic review was conducted in MEDLINE, EMBASE, Cochrane databases from inception through September 2017 to identify studies that evaluate the risk of AF in adults with short sleep duration, long sleep duration, insomnia and/or frequent awakening. Effect estimates from the individual study were extracted and combined using random-effect, generic inverse variance method of DerSimonian and Laird.Results: Ten observational studies (14 296 314 patients) were enrolled. The pooled odds ratios (ORs) of AF in individuals with short sleep (< 6 h) and long sleep (> 8 h) were 1.20 (95% confidence interval (CI) 0.93-1.55, I-2 = 66%) and 1.24 (95% CI 0.96-1.62, I-2 = 58%), respectively. There was no association between increase in sleep duration and AF, with a pooled OR of 0.97 (95% CI 0.84-1.12, I-2 = 0%). However, there were significant associations of AF with insomnia and frequent awakening, with pooled ORs of 1.30 (95% CI 1.26-1.35, I-2 = 3%) and 1.36 (95% CI 1.13-1.63, I-2 = 55%), respectively.Conclusions: Our findings suggest an absence in association between AF and sleep duration but reveal the potential association between AF and both insomnia and frequent nocturnal awakening. As such, the further studies on association of AF and sleep qualities are warranted.