CHANGES IN THE CLINICAL FEATURES AND PROGNOSTIC FACTORS OF ENDOGENOUS ENDOPHTHALMITIS Fifteen Years of Clinical Experience in Korea
CHANGES IN THE CLINICAL FEATURES AND PROGNOSTIC FACTORS OF ENDOGENOUS ENDOPHTHALMITIS Fifteen Years of Clinical Experience in Korea
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DOI：
10.1097/iae.0b013e318228e312
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发表时间：
2012-05-01
影响因子：
3.3
通讯作者：
Lee, Joo Yong
中科院分区：
文献类型：
--
作者：
Lee, Suhwan;Um, Taewoong;Lee, Joo Yong
目的：了解1996年至2010年韩国内源性眼内炎的临床特征、治疗和预后因素的变化。方法：回顾性分析1996年1月至2010年12月诊断为内源性眼内炎患者的病历，分为1996年至2000年、2001年至2005年、2006年至2010年3个时期。变量包括年龄、感染源、全身状况、初始和最终视力、致病生物和治疗。结果：眼内炎80例（97眼）。糖尿病（42.5%）和肝硬化（20%）是这些患者常见的全身性疾病。肝脓肿是眼内炎最常见的感染灶（25%）。肺炎克雷伯菌（48.4%）是常见的病原体，尽管最近革兰氏阳性球菌引起的眼内炎的频率有所增加。在过去的5年中，玻璃体切除术作为初始治疗的使用有所增加。良好的初始视力大于数指（P < 0.001），早期玻璃体切除术患者初始视力良好（P = 0.035），革兰氏阳性球菌（P = 0.033）作为病原体与视力成功预后显著相关。结论：虽然大多数内源性眼内炎患者的预后普遍较差，但如果治疗得当，早期治疗，部分眼睛可获得较好的视力结果。视网膜32:97 -984,2012
Purpose: To identify changes in the clinical features, management, and prognostic factors of endogenous endophthalmitis in Korea from 1996 through 2010.Methods: We conducted a retrospective review of medical records of patients diagnosed with endogenous endophthalmitis from January 1996 to December 2010, which was divided into 3 periods: 1996 to 2000, 2001 to 2005, and 2006 to 2010. Variables included age, source of infection, systemic conditions, initial and final visual acuities, causative organisms, and treatment.Results: Endophthalmitis was identified in 80 patients (97 eyes). Diabetes (42.5%) and liver cirrhosis (20%) were the common systemic problems in these patients. Liver abscess (25%) was the most common infection focus of the endophthalmitis. Klebsiella pneumoniae (48.4%) was the common causative agent, although more recently, endophthalmitis caused by gram-positive cocci has increased in frequency. The use of vitrectomy as an initial treatment has increased during the past 5 years. Good initial visual acuity greater than counting fingers (P < 0.001), early vitrectomy in patients with initially good visual presentation (P = 0.035), and gram-positive cocci (P = 0.033) as a causative agent were significantly related to a successful visual outcome.Conclusion: Although the prognosis of endogenous endophthalmitis is generally poor in most patients, some eyes can have relatively good visual outcomes if treated appropriately and early enough. RETINA 32:977-984, 2012