PROTEOGLYCAN CONTENT AND AXIAL PERIODICITY OF COLLAGEN IN TENDON
PROTEOGLYCAN CONTENT AND AXIAL PERIODICITY OF COLLAGEN IN TENDON
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DOI：
10.1042/bj1630145
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发表时间：
1977-01-01
影响因子：
4.1
通讯作者：
FLINT, MH
中科院分区：
文献类型：
--
作者：
GILLARD, GC;MERRILEES, MJ;FLINT, MH
测定了兔趾深屈肌腱不同部位的糖胺多糖含量和胶原蛋白的轴向周期性。这条肌腱从小腿绕着脚踝内侧传到脚趾，在那里它受到摩擦和压力，含有一个增厚的种子样垫。肌腱的其他区域只受纵向张力的影响。在张力区，胶原的轴向周期约为62 nm，组织中蛋白多糖的干重低于0.2%。在类籽粒区域，轴向周期显著减少13-15%，蛋白多糖约占干重的3.5%。此外，在张力区，主要的糖胺聚糖是硫酸皮肤素，但在籽粒中，主要的糖胺聚糖是硫酸软骨素。讨论了胶原轴周期性与组织中蛋白多糖含量之间可能的相互关系。
The glycosaminoglycan content and the axial periodicity of collagen was determined in various regions of the rabbit flexor digitorum profundus tendon. This tendon, which passes from the calf to the toes round the inner side of the ankle, contains a thickened sesamoid-like pad where it is subjected to friction and pressure. Other regions of the tendon are subject only to longitudinal tension. In tensional areas the axial periodicity of collagen was of the order of 62 nm and the tissue contained less than 0.2% proteoglycan on a dry weight basis. In the sesamoid-like region, the axial periodicity was a significant 13-15% less, and the proteoglycan constituted about 3.5% of the dry weight. Also, in the tensional areas the predominant glycosaminoglycan was dermatan sulfate, but in the sesamoid the predominant glycosaminoglycan was chondroitin sulfate. The possible interrelationships between collagen axial periodicity and proteoglycan content in this tissue are discussed.