Visual cortical input alters spatial tuning in monkey lateral geniculate nucleus cells.
Visual cortical input alters spatial tuning in monkey lateral geniculate nucleus cells.
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DOI：
10.1113/jphysiol.1984.sp015103
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发表时间：
1984-03
期刊：
影响因子：
--
通讯作者：
J. W. McClurkin;R. Marrocco
中科院分区：
文献类型：
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作者：
J. W. McClurkin;R. Marrocco
本实验观察了猴外侧膝状体核（l.g.n.）用钨微电极记录细胞对闪光点、环带和漂移正弦波光栅的反应。这些刺激（a）通过径向光栅中心的孔径单眼地呈现，或（B）双视地呈现，其中斑点或漂移光栅呈现给优势眼的感受野，而径向光栅的中心定位在另一只眼的相应视网膜位置上。径向光栅的移动产生了l.g.n.的变化。由斑点和正弦波光栅引起的细胞反应这些变化被逆转的纹状皮质冷冻封锁。因此，径向光栅移动改变l.g.n.的响应。通过激活皮质膝状体（c.g.）通路在大约一半的细胞中，产生了径向光栅诱导的中心或周围或对斑点和环的反应的改变。通过采用中心和环绕机制的简单空间滤波模型，可以预测中心/环绕平衡的这些改变将如何影响细胞对正弦波光栅的响应。在空间和/或时间调谐曲线的峰值和带宽中观察到改变。径向光栅没有改变细胞的空间总和特性。在光谱中性点的染色对手的神经元偶尔发现轻微的alterations。这些结果被解释为支持的观点，即空间和时间的调谐是一些l.g.n.的动态特性。通过视觉皮层的下行输入来控制神经元。
The response of monkey lateral geniculate nucleus (l.g.n.) cells to flashing spots, annuli, and drifting sine‐wave gratings were recorded with tungsten micro‐electrodes. These stimuli were presented (a) monocularly, through an aperture in the centre of a radial grating, or (b) dichoptically, in which the spots or drifting gratings were presented to the dominant eye's receptive field, while the centre of the radial grating was positioned on the corresponding retinal location of the other eye. Movement of the radial grating produced changes in the l.g.n. cell responses evoked by the spots and sine‐wave gratings. These changes were reversed by cryogenic blockade of the striate cortex. Therefore, radial grating movement altered the responses of l.g.n. cells by activating the corticogeniculate (c.g.) pathway. In about half of all cells, radial grating‐induced alterations of centre, or surround, or both responses to spots and annuli were produced. By adopting a simple spatial filtering model of the centre and surround mechanisms, it was possible to predict how these alterations in centre/surround balance would affect the cell's responses to sine‐wave gratings. Alterations were observed in the peak and band width of the spatial and/or temporal tuning curves. The radial gratings did not alter the spatial summation properties of cells. Minor alterations in the spectral neutral points of chromatically opponent neurones were occasionally found. These results are interpreted as support for the view that spatial and temporal tuning are dynamic properties of some l.g.n. neurones by virtue of descending input from the visual cortex.