Pain inhibition, nicotine, and gender.
Pain inhibition, nicotine, and gender.
复制标题
疼痛抑制、尼古丁和性别。
DOI：
10.1037//1064-1297.6.1.96
复制
发表时间：
1998
期刊：
影响因子：
--
通讯作者：
Jarvik,ME
中科院分区：
文献类型：
--
作者：
Jamner,LD;Girdler,SS;Shapiro,D;Jarvik,ME
尼古丁降低人类对疼痛的敏感性的能力一直是一个有争议的话题。在涉及男性的研究中，敏感性降低了，而在主要涉及或完全涉及女性的研究中，这种影响就不那么明显或没有了。为了确定尼古丁的减痛作用是否存在性别差异，在安慰剂和尼古丁条件下，对30名男性和44名女性吸烟者和非吸烟者进行了皮肤电刺激评分。尼古丁提高了男性的疼痛阈值和耐受性评级，但对女性的疼痛评级没有影响。在男性中，吸烟史没有影响，这表明疼痛感知的变化反映了尼古丁对疼痛的直接抑制作用，而不是对急性尼古丁戒断的缓解。尼古丁对情绪或任务评级没有影响，表明观察到的抗伤害效应不是由于尼古丁假定的情绪影响。(心理信息数据库记录(C)2016 APA，保留所有权利)
The ability of nicotine to decrease sensitivity to pain in humans has been a subject of dispute. Decreased sensitivity has been demonstrated in studies involving men, whereas the effect has been less obvious or absent in studies involving predominantly, or entirely, women. To determine whether there are gender differences in nicotine's hypoalgesic actions, ratings of electrocutaneous stimulation were obtained from 30 male and 44 female smokers and nonsmokers under placebo and nicotine conditions. Nicotine increased the pain threshold and tolerance ratings of men but had no effect on the pain ratings of women. Among men, there was no effect of smoking history, suggesting that the changes in pain perception reflect a direct pain-inhibitory effect of nicotine rather than a relief from acute nicotine withdrawal. Nicotine had no effect on mood or task ratings, indicating that the antinociceptive effects observed were not due to nicotine's putative mood effects.(PsycINFO Database Record (c) 2016 APA, all rights reserved)