Upper and Lower Urinary Tract Outcomes in Adult Myelomeningocele Patients: A Systematic Review
Upper and Lower Urinary Tract Outcomes in Adult Myelomeningocele Patients: A Systematic Review
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DOI：
10.1371/journal.pone.0048399
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发表时间：
2012-10-31
期刊：
影响因子：
3.7
通讯作者：
de Kort, Laetitia M. O.
中科院分区：
文献类型：
--
作者：
Veenboer, Paul W.;Bosch, J. L. H. Ruud;de Kort, Laetitia M. O.
背景资料：膀胱功能障碍和脑积水的复杂治疗的引入允许大多数SB患者存活到成年。然而，没有系统的审查泌尿系统的结果在成人SB patients是可用的，没有后续schemesexist. Objective. To系统地总结证据的结果尿路功能在成人SB patients.Methods：PubMed和Embase数据库中的文献检索。仅纳入过去25年发表的描述平均年龄>18岁的开放性SB患者的论文。我们专注于发现治疗策略的差异，例如。例如，在一个实施例中，结果：共发现13篇关于成人SB患者尿路状态的文章和5篇会议摘要，共描述了1564例患者，平均年龄为26.1岁（范围3-74岁，少数患者
Background: The introduction of sophisticated treatment of bladder dysfunction and hydrocephalus allows the majority of SB patients to survive into adulthood. However, no systematic review on urological outcome in adult SB patients is available and no follow-up schemes exist.Objectives: To systematically summarize the evidence on outcome of urinary tract functioning in adult SB patients.Methods: A literature search in PubMed and Embase databases was done. Only papers published in the last 25 years describing patients with open SB with a mean age >18 years were included. We focused on finding differences in the treatment strategies, e. g., clean intermittent catheterization and antimuscarinic drugs versus early urinary diversion, with regard to long-term renal and bladder outcomes.Results: A total of 13 articles and 5 meeting abstracts on urinary tract status of adult SB patients were found describing a total of 1564 patients with a mean age of 26.1 years (range 3-74 years, with a few patients