Long-term exposure to low levels of formaldehyde increases the number of tyrosine hydroxylase-immunopositive periglomerular cells in mouse main olfactory bulb
Long-term exposure to low levels of formaldehyde increases the number of tyrosine hydroxylase-immunopositive periglomerular cells in mouse main olfactory bulb
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DOI：
10.1016/j.brainres.2003.12.052
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发表时间：
2004-05
期刊：
影响因子：
2.9
通讯作者：
H. Hayashi;N. Kunugita;K. Arashidani;H. Fujimaki;M. Ichikawa
中科院分区：
文献类型：
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作者：
H. Hayashi;N. Kunugita;K. Arashidani;H. Fujimaki;M. Ichikawa
对长期低水平化学品暴露的多种化学品敏感性（MCS）是一种尚未明确的疾病。为了确定嗅觉功能在诱导MCS中的作用，在小鼠暴露于低水平甲醛后，对主要嗅球（MOB）进行免疫细胞化学分析。长期暴露导致酪氨酸羟化酶免疫阳性肾小球周围细胞数量增加，并可能影响MOB的神经元功能。
Multiple chemical sensitivity (MCS) in response to a long-term low-level chemical exposure is as yet an unclarified disorder. To determine the role of olfactory function in the induction of MCS, immunocytochemical analysis of the main olfactory bulb (MOB) was performed after exposure of mice to low levels of formaldehyde. A long-term exposure resulted in an increase in the number of tyrosine hydroxylase-immunopositive periglomerular cells and may affect the neuronal function of the MOB.