TARGETED RELAXATION ENHANCEMENT AGENTS FOR MRI
TARGETED RELAXATION ENHANCEMENT AGENTS FOR MRI
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DOI：
10.1002/mrm.1910220237
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发表时间：
1991-12-01
影响因子：
3.3
通讯作者：
LAUFFER, RB
中科院分区：
文献类型：
--
作者：
LAUFFER, RB
简要讨论了靶向弛豫增强剂（一种新型MRI造影剂）的设计、相对优点和初步应用。这些试剂被设计为可逆地结合到感兴趣的组织中的靶大分子，从而增强水质子弛豫效率和MRI对比度。靶向药物的最初应用包括血池和肝胆成像。出版社：Academic Press，Inc.
The design, relative merits, and initial applications of targeted relaxation enhancement agents, a new form of MRI contrast media, are briefly discussed. These agents are designed to bind reversibly to target macromolecules in a tissue of interest, thus enhancing water proton relaxation efficiency and MRI contrast. Initial applications for targeted agents include blood pool and hepatobiliary imaging. © 1991 Academic Press, Inc.