Slower processing speed after treatment for pediatric brain tumor and acute lymphoblastic leukemia
Slower processing speed after treatment for pediatric brain tumor and acute lymphoblastic leukemia
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DOI：
10.1002/pon.3255
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发表时间：
2013-09-01
期刊：
影响因子：
3.6
通讯作者：
Hinds, Pamela S.
中科院分区：
文献类型：
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作者：
Kahalley, Lisa S.;Conklin, Heather M.;Hinds, Pamela S.
Background Acute lymphoblastic leukemia (ALL) and brain tumor (BT) survivors are at risk for post-treatment IQ declines. The extent to which lower scores represent global cognitive decline versus domain-specific impairment remains unclear. This study examined discrepancies between processing speed and estimated IQ (EIQ) scores and identified clinical characteristics associated with score discrepancies in a sample of pediatric cancer survivors. Procedure Survivors (50 ALL, 50 BT) ages 12-17years completed cognitive testing. The Wechsler Abbreviated Scale of Intelligence provided an untimed measure of general reasoning ability (EIQ). The age-appropriate Wechsler Intelligence Scale provided a Processing Speed Index (PSI) score. Scores were examined and compared. Results Survivors' PSI scores were lower than their EIQ scores (BT t(45)=6.3, p
