GRANULAR CELLS OF GALLERIA-MELLONELLA DURING CLOTTING AND PHAGOCYTIC REACTIONS INVITRO
GRANULAR CELLS OF GALLERIA-MELLONELLA DURING CLOTTING AND PHAGOCYTIC REACTIONS INVITRO
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DOI：
10.1016/0040-8166(76)90004-5
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发表时间：
1976-01-01
期刊：
影响因子：
2.6
通讯作者：
RATCLIFFE, NA
中科院分区：
文献类型：
--
作者：
ROWLEY, AF;RATCLIFFE, NA
Light microscopic and EM observations of the blood-cells (hemocytes) of the wax-moth G. mellonella showed that hemolymph coagulation was initiated by the rapid release of material from the granular cells. During incubation for short terms in vitro these cells showed progressive degranulation as material derived from the granules was discharged into the hemolymph. Attempts to determine the nature of this material by staining with ruthenium red proved mainly unsuccessful. When challenged with bacteria in vitro the granular cells failed to phagocytoze these particles and instead the bacteria became embedded in the granular material surrounding these cells. The mode of coagulation reported is compared with previous reports of the role of invertebrate hemocytes in hemolymph clotting.
