Vaginal douching and reduced fertility
Vaginal douching and reduced fertility
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DOI：
10.2105/ajph.86.6.844
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发表时间：
1996-06-01
影响因子：
12.7
通讯作者：
Daling, JR
中科院分区：
文献类型：
--
作者：
Baird, DD;Weinberg, CR;Daling, JR
目标。本研究调查了灌水和降低生育力。在华盛顿州金县的840名已婚产妇的样本中，比较了冲水者和不冲水者每月受孕的概率。对怀孕所需月数的数据进行了分析。与不使用冲洗器的妇女相比，冲洗器的妇女每尝试怀孕一个月怀孕的可能性降低30%。在对协变量进行调整后，这种关系仍然存在，这不能用女性因医学原因冲洗来解释。减少与所使用的冲洗制剂的类型无关。与老年女性相比，冲洗过的年轻女性每月生育率的下降幅度更大(18至24岁女性下降50%，25至29岁女性下降29%，30至39岁女性下降6%)。冲洗与生育力下降有关。需要进一步的研究来确定这种关系是否是因果关系，如果是的话，它在多大程度上是由盆腔炎介导的。与此同时，女性应该被告知，冲洗可能会产生不良影响。
Objectives. This study investigated douching and reduced fertility.Methods. The monthly probability of conception for douchers and nondouchers was compared in a sample of 840 married, parous women in King County, Washington. Data on the number of months required to conceive were analyzed.Results. In comparison with nondouchers, women who douched were 30% less likely to become pregnant each month they attempted pregnancy. This relationship remained after adjustment for covariates, and it could not be explained by women douching for medical reasons. The reduction was not related to the type of douching preparation used. Young women who douched had significantly greater reductions in monthly fertility than older women (50% reduction for women 18 to 24 years old, 29% reduction for women 25 to 29 years old, and 6% reduction for women 30 to 39 years old).Conclusions. Douching was associated with reduced fertility. Further research is needed to determine whether the relationship is causal and, if so, to what extent it is mediated by pelvic infection. In the meantime, women should be informed that douching may have adverse effects.