IGE IN HUMAN ECCRINE SWEAT

IGE IN HUMAN ECCRINE SWEAT
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DOI:
10.1111/1523-1747.ep12533312
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发表时间:
1975-01-01
影响因子:
6.5
通讯作者:
WINKELMANN, RK
WINKELMANN, RK
中科院分区:
医学1区
文献类型:
--
作者:
FORSTROM, L;GOLDYNE, ME;WINKELMANN, RK

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通过使用一个敏感和特异性的双抗体放射免疫分析,免疫球蛋白E被证明在汗液中从11名健康志愿者6; IgE的浓度范围从1到3.9毫微克/毫升的汗水。7例皮炎和血清IgE水平升高的患者中有6例在汗液中也有高IgE水平;汗液中的最高IgE值为75.5 ng/ml,并在特应性皮炎患者中观察到。因此,所有主要的免疫球蛋白类别都可以在外分泌汗液中显示出来。
By the use of a sensitive and specific double antibody radioimmunoassay, immunoglobulin E was demonstrated in sweat from 6 of 11 healthy volunteers; the concentrations of IgE ranged from 1 to 3.9 ng/ml of sweat. Six of seven patients with dermatitis and elevated levels of serum IgE also had high IgE levels in sweat; the highest IgE value in sweat was 75.5 ng/ml and was noted in a patient with atopic dermatitis. Thus, all the main immunoglobulin classes can he demonstrated in eccrine sweat.