Pupil evaluation as a test for autonomic disorders
Pupil evaluation as a test for autonomic disorders
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DOI：
10.1007/s10286-009-0515-2
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发表时间：
2009-04-01
影响因子：
5.8
通讯作者：
Bremner, Fion
中科院分区：
文献类型：
--
作者：
Bremner, Fion
瞳孔检查为自主神经功能的评价提供了一种方便、简便的方法。大多数自主神经障碍患者表现出交感或副交感神经缺陷的证据，这些可以通过临床体征、瞳孔测量测试(测量对光线、调节努力或突然的噪音的反应)和药理学测试(使用局部应用的药物来确认缺陷和定位损害)来检测。在解释这些测试时需要谨慎，特别是如果缺陷是混合的(即交感和副交感)或双侧。学生的自主神经障碍模式通常与其他地方的自主神经功能相关性较差，但在区分不同的潜在疾病方面可能有诊断价值。
Pupil tests provide a convenient and simple method for evaluation of autonomic function. Most patients with autonomic disorders show evidence of sympathetic or parasympathetic deficits in the pupil, and these can be detected using a combination of clinical signs, pupillometric tests (measuring the responses to light, or an accommodative effort, or a sudden noise) and pharmacological tests (using topically applied drugs both to confirm a deficit and to localize the lesion). Caution is needed in the interpretation of these tests, particularly if the deficits are mixed (i.e. sympathetic and parasympathetic) or bilateral. The pattern of autonomic disturbance in the pupils often correlates poorly with autonomic function elsewhere, but may have diagnostic value in discriminating between different underlying conditions.