Construct validity of the NIH Toolbox Cognition Battery in individuals with stroke.

Construct validity of the NIH Toolbox Cognition Battery in individuals with stroke.
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DOI:
10.1037/rep0000195
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发表时间:
2017-11
影响因子:
2.7
通讯作者:
Heinemann AW
Heinemann AW
中科院分区:
医学3区
文献类型:
--
作者:
Carlozzi NE;Tulsky DS;Wolf TJ;Goodnight S;Heaton RK;Casaletto KB;Wong AWK;Baum CM;Gershon RC;Heinemann AW

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美国国立卫生研究院(NIH)行为和神经功能认知成套测验(NIHTB-CB)提供了对认知关键组成部分的简要评估(约30分钟)。本文探讨了结构效度,以支持NIHTB-CB在中风患者中的临床应用。共有131名卒中患者(n = 71名轻度卒中; n = 60名中度/重度卒中)完成了NIHTB-CB。进行单变量分析,以检查两个不同卒中组(轻度与中度/重度卒中)的NIHTB-CB测量和综合评分的认知特征。Pearson相关NIHTB-CB和既定的措施,以检查收敛和判别效度之间进行。还检查了不同NIHTB-CB指标和综合评分的效应大小和临床损伤率。在NIHTB的几项认知测量中,经历中度至重度中风的参与者比轻度中风的个体表现更差。NIHTB测量和相应的标准神经心理学测试之间的中度至强相关性提供了收敛效度的证据(Pearson rs范围为0.31至0.88;中位数= 0.60)。不同认知领域之间的相关性比同一领域内的措施的相关性更小的判别效度的证据。关于卒中严重程度的复合和分测验评分的效应量通常为中到大。此外,42%的样本表现出轻度认知障碍(即,液体检查≥2分低)。研究结果为NIHTB-CB在中风患者中的结构效度提供了支持。
The National Institutes of Health (NIH) Toolbox (NIHTB) for the Assessment of Behavior and Neurological Function Cognition Battery (NIHTB-CB) provides a brief assessment (approximately 30 min) of key components of cognition. This article examines construct validity to support the clinical utility of the NIHTB-CB in individuals with stroke. A total of 131 individuals with stroke (n = 71 mild stroke; n = 60 moderate/severe stroke) completed the NIHTB-CB. Univariate analyses were conducted to examine the cognitive profiles of the two different stroke groups (mild vs. moderate/severe stroke) on NIHTB-CB measures and composite scores. Pearson correlations were conducted between NIHTB-CB and established measures to examine convergent and discriminant validity. Effect sizes and clinical impairment rates for the different NIHTB-CB measures and composite scores were also examined. Participants experiencing moderate to severe stroke had poorer performance than did individuals with mild stroke on several of the NIHTB cognition measures. Evidence of convergent validity was provided by moderate to strong correlations between the NIHTB measures and the corresponding standard neuropsychological test (Pearson rs ranged from 0.31 to 0.88; median = .60). Evidence of discriminant validity was provided by smaller correlations between different cognitive domains than correlations of measures within the same domain. Effect sizes for composite and subtest scores regarding stroke severity were generally moderate-to-large. In addition, 42% of the sample were exhibiting mild cognitive impairment (i.e., ≥2 low scores on fluid tests). Findings provide support for the construct validity of the NIHTB-CB in individuals with stroke.
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