Effects on birth weight and perinatal mortality of maternal dietary supplements in rural Gambia: 5 year randomised controlled trial

Effects on birth weight and perinatal mortality of maternal dietary supplements in rural Gambia: 5 year randomised controlled trial
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DOI:
10.1136/bmj.315.7111.786
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发表时间:
1997-09-27
影响因子:
105.7
通讯作者:
Whitehead, RG
Whitehead, RG
中科院分区:
医学1区
文献类型:
--
作者:
Ceesay, SM;Prentice, AM;Whitehead, RG

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目的:通过初级卫生保健系统测试非洲孕妇膳食补充剂计划对出生体重和婴儿存活率的效果。设计:对 28 个村庄的所有孕妇进行为期 5 年的对照试验,随机每天补充高能量花生饼干(4.3MJ/天),持续约 20 周,时间为产前(干预)或产后(对照)。地点:冈比亚农村 受试者:长期营养不良的妇女(不包括双胞胎), 2047 例单胎活产和 35 例死产。主要结局指标:出生体重;低出生体重的患病率(
Objective: To test the efficacy in terms of birth weight and infant survival of a diet supplement programme in pregnant African women through a primary healthcare system.Design: 5 year controlled trial of all pregnant women in 28 villages randomised to daily supplementation with high energy groundnut biscuits (4.3MJ/day) for about 20 weeks before delivery (intervention) or after delivery (control).Setting: Rural GambiaSubjects: Chronically undernourished women (twin bearers excluded), yielding 2047 singleton live births and 35 stillbirths.Main outcome measures: Birth weight; prevalence of low birth weight (