Crystallization of Amphiphilic DNA C-Stars
Crystallization of Amphiphilic DNA C-Stars
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DOI：
10.1021/acs.nanolett.7b00980
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发表时间：
2017-05-01
期刊：
影响因子：
10.8
通讯作者：
Di Michele, Lorenzo
中科院分区：
文献类型：
--
作者：
Brady, Ryan A.;Brooks, Nicholas J.;Di Michele, Lorenzo
许多新兴技术需要具有明确定义的三维纳米结构的材料。这些结构的产生目前是由自组装的两亲性大分子或工程化的全DNA构建块支撑的。这两种方法都产生有限的晶体几何形状范围，由于合成的两亲物简单的形状和有限的特异性，或在设计具有目标形状的空间填充DNA基序的技术困难。我们已经克服了这些限制与两亲性DNA纳米结构，或C-Stars，结合联合收割机的设计自由度和基于DNA的材料与强大的疏水相互作用的简易功能化。C-Stars自组装成尺寸超过40 μ m的单晶，晶格参数超过20 nm。
Many emerging technologies require materials with well-defined three-dimensional nanoscale architectures. Production of these structures is currently underpinned by self-assembling amphiphilic macromolecules or engineered all-DNA building blocks. Both of these approaches produce restricted ranges of crystal geometries due to synthetic amphiphiles simple shape and limited specificity, or the technical difficulties in designing space-filling DNA motifs with targeted shapes. We have overcome these limitations with amphiphilic DNA nanostructures, or C-Stars, that combine the design freedom and facile functionalization of DNA-based materials with robust hydrophobic interactions. C-Stars self-assemble into single crystals exceeding 40 mu m in size with lattice parameters exceeding 20 nm.