Neurocognitive functioning and quality of life among dually diagnosed and non-substance abusing schizophrenia inpatients
Neurocognitive functioning and quality of life among dually diagnosed and non-substance abusing schizophrenia inpatients
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DOI：
10.1111/j.1440-0979.2004.00346.x
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发表时间：
2004-12-01
影响因子：
5.6
通讯作者：
Herman, Michael
中科院分区：
文献类型：
--
作者：
Herman, Michael
本研究的目的是比较的智力，记忆和执行功能的精神分裂症的人同时有物质滥用障碍（双重诊断）与一组非物质滥用精神分裂症患者的域，并确定是否有两组之间的差异，他们的看法生活质量。本文对46例精神分裂症双重诊断者和43例非物质滥用者的神经心理学和生活质量进行了回顾性分析。所有受试者均为州立精神病医院的住院患者。选定的韦氏成人智力量表- III和韦氏记忆量表- III的子测试构成的智力和记忆的措施，而执行功能的措施是Stroop颜色词测试，FAS版本的控制口头词联想测试，和连线测试（线索A和B）。使用世界卫生组织的生活质量测量来评估对生活质量的感知。两组在智力和记忆领域没有区别，但是，双重诊断显示出更好的执行功能任务的设施。此外，与非药物滥用的精神分裂症患者相比，双重诊断者对其生活质量的满意度更高。这些结果对干预措施有影响。
The aim of this study was to compare the domains of intellectual, memory and executive functions of persons with schizophrenia who concurrently have substance abuse disorders (the dually diagnosed) with a group of non-substance-abusing patients with schizophrenia and to ascertain if there were differences between the two groups in their perceptions of quality of life. Neuropsychological and quality of life data of 46 dually diagnosed and 43 non-substance-abusing patients with schizophrenia was analysed retrospectively. All subjects were inpatients of a state psychiatric hospital. Selected subtests of the Wechsler Adult Intelligence Scale - III and the Wechsler Memory Scale - III constituted the intellectual and memory measures whilst the measures of executive functioning were the Stroop Color Word Test, the FAS version of the Controlled Oral Word Association Test, and the Trail Making Test (Trails A & B). Perceptions of quality of life were evaluated using the World Health Organization Quality of Life measure. The two groups did not differentiate on intellectual and memory domains, however, the dually diagnosed showed a significantly better facility with tasks of executive functions. In addition, the dually diagnosed expressed higher levels of satisfaction with their quality of life compared to the non-substance-abusing patients with schizophrenia. These results have implications for interventions.