MORPHOLOGICAL-CHANGES OF THE SPIRAL ARTERIES IN THE PLACENTAL BED IN RELATION TO PRE-ECLAMPSIA AND FETAL GROWTH-RETARDATION
MORPHOLOGICAL-CHANGES OF THE SPIRAL ARTERIES IN THE PLACENTAL BED IN RELATION TO PRE-ECLAMPSIA AND FETAL GROWTH-RETARDATION
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DOI：
10.1111/j.1471-0528.1981.tb02222.x
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发表时间：
1981-01-01
期刊：
影响因子：
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通讯作者：
ELEMA, JD
中科院分区：
文献类型：
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作者：
GERRETSEN, G;HUISJES, HJ;ELEMA, JD
对93例人胎盘床蜕膜-子宫肌层连接处的螺旋动脉进行了组织学检查。其中23例来自正常的无并发症妊娠，30例来自先兆子痫，40例来自其他并发症妊娠。正如Brosens等人所指出的那样，螺旋动脉的生理变化与无并发症妊娠和子痫前期不存在的关联得到了证实。在没有先兆子痫的妊娠中，这些变化在胎儿生长迟缓时更为明显。显然，妊娠期高血压是一种代偿机制，以确保在生理变化未能发生时胎盘有足够的血液供应。
The spiral arteries at the level of the decidual-myometrial junction in the [human] placental bed were examined histologically in 93 biopsies. Of these, 23 originated from normal uncomplicated pregnancies, 30 from pre-eclamptic and 40 from otherwise complicated pregnancies. The association of the pbysiological changes of the spiral artery with uncomplicated pregnancy and their absence in pre-eclampsia, as noted by Brosens and others, was confirmed. In pregnancies without pre-eclampsia, these changes were significantly more often absent with fetal growth retardation. Apparently, hypertension of pregnancy is a compensatory mechanism to ensure an adequate blood supply to the placenta when the physiological changes fail to occur.