Toxic metabolites of Amanita pantherina, A. cothurnata, A. muscaria and other Amanita species.
Toxic metabolites of Amanita pantherina, A. cothurnata, A. muscaria and other Amanita species.
复制标题
豹伞菌 (Amanita pantherina)、cothurnata、毒蝇伞 (A. muscaria) 和其他伞菌属物种的有毒代谢物。
DOI：
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发表时间：
1976
期刊：
影响因子：
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通讯作者：
J. Ott
中科院分区：
文献类型：
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作者：
W. Chilton;J. Ott
对鹅膏菌属(Amanita)35个种或变种的47个标本进行了鹅膏酸、蝇草醇、二茂铁酸、二茂铁酸、氨基己二烯酸和氯化十六烷基甘氨酸的检测。此外，还用层析法检测了番木香的粗提物中是否含有甲基四烃基甲酸(MTC)。冬虫夏草的提取物、苍耳子草的所有标本、黄花冬虫夏草的所有标本中都含有明显浓度的鹅膏烯酸和蝇草酚，而在天冬虫草的提取物中检测到较低的浓度。在一个变种的苍耳中发现了可检测到的浓度，在所有的白僵菌样品中都发现了可检测到的浓度，在对提取物进行进一步纯化后，在金鱼和其余样品中也发现了痕量的二茂铁酸和二茂铁酸。仅在黑曲霉粗提物中检测到氨基己二烯酸和氯化十六烷基甘氨酸。在蘑菇粗提物中未检出MTC。从华盛顿州西部采集的17公斤美洲斑潜蝇标本中分离得到结晶鹅掌酸(820 Mg)。
Forty-seven specimens representing 35 species or varieties of Amanita were examined for the presence of ibotenic acid, muscimol, stizolobic acid, stizolobinic acid, aminohexadienoic acid and chlorocrotylglycine. In addition, crude extracts of A. muscaria were examined chromatographically for the presence of methyltetrahydrocarboline carboxylic acid (MTC). Ibotenic acid and muscimol were found in clearly detectable concentrations in extracts of A. cothurnata, all specimens of A. muscaria, all specimens of A. pantherina and in lower concentrations in A. gemmata. Stizolobic acid and stizobinic acid were found in detectable concentrations in one variety of A. muscaria, in all specimens of A. pantherina and in trace levels after additional purification of the extracts in A. gemmata and in the remaining specimens of A. muscaria. Aminohexadienoic acid and chlorocrotylglycine were detected only in crude extracts of A. smithiana. MTC could not be detected in crude extracts of A. muscaria. Crystalline ibotenic acid (820 mg) was isolated from 17 kg of a specimen of A. pantherina collected in western Washington State.