Bile duct ligation increased dopamine levels in the cerebral cortex of rats partly due to induction of tyrosine hydroxylase
Bile duct ligation increased dopamine levels in the cerebral cortex of rats partly due to induction of tyrosine hydroxylase
复制标题
胆管结扎增加大鼠大脑皮层多巴胺水平，部分原因是诱导酪氨酸羟化酶
DOI：
10.1111/bph.16041
复制
发表时间：
2023-02-13
影响因子：
7.3
通讯作者：
Liu, Li
中科院分区：
文献类型：
--
作者：
Kong, Weimin;Sun, Xueying;Liu, Li
肝衰竭与精神改变有关，部分原因是大脑多巴胺水平升高。我们使用胆管结扎（BDL）大鼠研究了多巴胺水平增加与精神异常之间的关系，以及肝功能衰竭增加SH-SY 5 Y细胞中多巴胺水平的机制。
Liver failure is associated with psychiatric alterations, partly resulting from the increased brain dopamine levels. We investigated the relationship between increased dopamine levels and mental abnormalities using bile duct ligation (BDL) rats and the mechanism by which liver failure increased dopamine levels in SH‐SY5Y cells.