Patellofemoral joint biomechanics and tissue engineering.
Patellofemoral joint biomechanics and tissue engineering.
复制标题
髌股关节生物力学和组织工程。
DOI：
10.1097/01.blo.0000171542.53342.46
复制
发表时间：
2005
影响因子：
4.2
通讯作者：
Hung,ClarkT
中科院分区：
文献类型：
--
作者：
Ateshian,GerardA;Hung,ClarkT
髌股关节生物力学研究的最新进展为髌股关节疾病提供了有前途的诊断和治疗模式，例如通过非侵入性成像定量评估软骨病变，优化手术参数和潜在预测结果的手术程序的计算机模拟，以及用于治疗晚期退行性关节疾病的软骨组织工程。这些技术仍在开发中，其临床潜力仍然是一个持续的研究主题。我们回顾了我们在解决这些问题方面的一些进展，以及软骨力学和润滑在理解髌股关节手术和软骨组织工程方面的挑战中的重要作用。
Recent advances in the study of patellofemoral joint biomechanics have provided promising diagnosis and treatment modalities for patellofemoral joint disorders, such as quantitative assessment of cartilage lesions from noninvasive imaging, computer simulations of surgical procedures for optimizing surgical parameters and potentially predicting outcomes, and cartilage tissue engineering for the treatment of advanced degenerative joint disease. These technologies are still in development and their clinical potentials remain an ongoing topic of investigation. We review some of our progress in addressing these issues, and the important role of cartilage mechanics and lubrication in understanding the challenges regarding patellofemoral surgery and cartilage tissue engineering.