Impedance electrodes positioned on proximal portions of limbs quantify fluid compartments in dogs.
Impedance electrodes positioned on proximal portions of limbs quantify fluid compartments in dogs.
复制标题
位于四肢近端部分的阻抗电极可量化狗的液体隔室。
DOI：
10.1152/jappl.1991.70.5.2039
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发表时间：
1991
期刊：
影响因子：
--
通讯作者：
Wilmore,DW
中科院分区：
文献类型：
--
作者：
Scheltinga,MR;Helton,WS;Rounds,J;Jacobs,DO;Wilmore,DW
在麻醉犬四肢远端和近端用电极测量交流电流传导的体阻抗和电抗。根据在控制期内和静脉注射0.9%生理盐水后在30分钟间隔内获得的这些测量结果计算身体阻抗。用溴化法和重水稀释法分别测定细胞外(ECW)和全身水(TBW)。近端电极的基线阻抗与ECW(r=0.001.95，P<0.0 1)和TBW(r=0.80，P<0.0 2)相关。注入生理盐水后，近端电极阻抗显著下降(P<0.001.0 5)，远端电极阻抗无明显下降(P=0.0 6)。此外，ECW和TBW可以通过给药后近端阻抗的下降来估计(r=0.82，P<0.02；r=0.86，P<0.01)，但不能通过远端阻抗测量来估计。在评估犬的体液变化方面，近端放置的阻抗电极优于传统使用的远端电极。
Body resistance and reactance to the conduction of an alternating electrical current were measured using electrodes attached to distal and proximal portions of limbs in anesthetized dogs. Body impedance was calculated from these measurements obtained at 30-min time intervals during a control period and after intravenous administration of 0.9% saline. Extracellular (ECW) and total body water (TBW) were determined by bromide and heavy water dilution techniques, respectively. Baseline impedance obtained from proximal electrodes was related to ECW (r = 0.95, P less than 0.001) and TBW (r = 0.80, P less than 0.02). After saline infusion, proximal electrodes detected a significant fall in impedance (P less than 0.001), whereas distal electrodes did not (P = 0.06). Furthermore, ECW and TBW could be estimated from the drop of proximal impedance after this bolus infusion (r = 0.82, P less than 0.02, and r = 0.86, P less than 0.01, respectively), but not from distal impedance measurements. Proximally placed impedance electrodes are superior to traditionally used distal electrodes for assessment of body fluid changes in the dog.