Longitudinal associations between self-reported experiences of discrimination and depressive symptoms in young women and men post- myocardial infarction.
Longitudinal associations between self-reported experiences of discrimination and depressive symptoms in young women and men post- myocardial infarction.
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年轻女性和男性心肌梗死后自我报告的歧视经历与抑郁症状之间的纵向关联。
DOI：
10.1016/j.jpsychores.2019.109782
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发表时间：
2019
影响因子：
4.7
通讯作者：
Lewis,TenéT
中科院分区：
文献类型：
--
作者：
Saelee,Ryan;Vaccarino,Viola;Sullivan,Samaah;Hammadah,Muhammad;Shah,Amit;Wilmot,Kobina;Abdelhadi,Naser;Elon,Lisa;Pimple,Pratik;Kaseer,Belal;Levantsevych,Oleksiy;Bremner,JD;Lewis,TenéT
目的研究表明，心肌梗死（MI）后，60岁以下的女性比同龄男性有更多的抑郁症状和不良后果。确定在这一群体中造成抑郁症状性别差异的风险因素，可能对制定社会心理干预措施至关重要。歧视的经历可能是这一群体抑郁症状的重要相关因素；然而，对这种关系的研究主要是横断面的，并且集中在健康人群中。本研究探讨了一个年轻心肌梗死后队列中性别、歧视和抑郁症状之间的纵向关联。方法研究对象为心肌梗死和精神应激性缺血研究2中年轻（≤60 岁）心肌梗死后患者的313名成年人。在基线和6 个月的随访中，用贝克抑郁量表- ii测量抑郁症状，用10项版日常歧视量表评估歧视。使用线性回归模型评估歧视报告与抑郁症状之间的纵向关联，对社会人口特征、心理社会因素和健康状况指标进行了调整，并对性别差异进行了测试。结果平均年龄51.2岁，女性49.6%，非裔美国人69.5%。尽管在完全调整的模型中，性别歧视的相互作用具有轻微的显著性（p= .09），但研究结果表明，随着时间的推移，歧视报告的变化与抑郁症状之间的关联在女性中可能更为明显（β = 0.61，标准误差 = 0.15,p< ）。001)比男性(β = 0.27,标准误差 = 0.13,p = .033)。结论：随着时间的推移，歧视是年轻心肌梗死后人群抑郁症状的一个危险因素。
ObjectivesResearch suggests that following a myocardial infarction (MI), women under the age of 60 have more elevated depressive symptoms and adverse outcomes than similarly aged men. Identifying risk factors that contribute to gender differences in depressive symptoms among this group may be critical to the development of psychosocial interventions. Experiences of discrimination may be an important correlate of depressive symptoms in this group; however, studies of this relationship have largely been cross-sectional and focused on healthy populations. This study examines longitudinal associations among gender, discrimination, and depressive symptoms in a young post-MI cohort.MethodsParticipants were 313 adults from the Myocardial Infarction and Mental Stress Ischemia Study 2 of young (≤60 yrs) post-MI patients. At baseline and 6 month follow-up, depressive symptoms were measured with the Beck Depression Inventory-II and discrimination was assessed with the 10-item version Everyday Discrimination scale. Linear regression models were used to assess the longitudinal association between reports of discrimination and depressive symptoms adjusted for sociodemographic characteristics, psychosocial factors and health status indicators and tested for gender differences.ResultsThe mean age was 51.2, 49.6% were women, and 69.5% were African-American. Although the discrimination-by-gender interaction was marginally significant (p= .09) in the fully adjusted model, findings suggest that the association between changes in reports of discrimination and depressive symptoms over time may be more pronounced for women (β = 0.61, standard error = 0.15,p< .001) than men (β = 0.27, standard error = 0.13,p= .033).ConclusionOur findings suggest that discrimination is a risk factor for depressive symptoms in young post-MI populations over time.