Oxidation of Pharmaceuticals by Ferrate(VI) in Hydrolyzed Urine: Effects of Major Inorganic Constituents
Oxidation of Pharmaceuticals by Ferrate(VI) in Hydrolyzed Urine: Effects of Major Inorganic Constituents
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DOI：
10.1021/acs.est.9b00006
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发表时间：
2019-05-07
影响因子：
11.4
通讯作者：
Huang, Ching-Hua
中科院分区：
文献类型：
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作者：
Luo, Cong;Feng, Mingbao;Huang, Ching-Hua
销毁尿液中排出的药物是消除这些环境污染物的有效方法。然而，尿液含有高浓度的氯化物、铵和碳酸氢盐，这可能会阻碍治疗过程。本研究评估了高铁酸盐（VI）（（FeO_（42-））-O-VI，Fe（VI））氧化合成水解人尿中的药物（卡马西平（CBZ）、萘普生（NAP）、甲氧苄啶（TMP）和磺胺类抗生素（SA））的应用，并揭示了尿中主要无机成分的新作用。由于离子强度效应，氯离子会略微降低Fe（VI）对药物的去除率。未稀释的水解尿中的铵（0.5 M）具有较强的清除作用，但较低浓度（
Destruction of pharmaceuticals excreted in urine can be an efficient approach to eliminate these environmental pollutants. However, urine contains high concentrations of chloride, ammonium, and bicarbonate, which may hinder treatment processes. This study evaluated the application of ferrate(VI) ((FeO42-)-O-VI, Fe(VI)) to oxidize pharmaceuticals (carbamazepine (CBZ), naproxen (NAP), trimethoprim (TMP), and sulfonamide antibiotics (SAs)) in synthetic hydrolyzed human urine and uncovered new effects from urine's major inorganic constituents. Chloride slightly decreased pharmaceuticals' removal rate by Fe(VI) due to the ionic strength effect. Ammonium (0.5 M) in undiluted hydrolyzed urine posed a strong scavenging effect, but lower concentrations (