A direct-electrospinning process by combined electric field and air-blowing system for nanofibrous wound-dressings
A direct-electrospinning process by combined electric field and air-blowing system for nanofibrous wound-dressings
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DOI：
10.1007/s00339-007-4330-0
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发表时间：
2008-03-01
影响因子：
2.7
通讯作者：
Yoon, Hyeon
中科院分区：
文献类型：
--
作者：
Kim, Geun Hyung;Yoon, Hyeon
介绍了一种制备具有高孔隙率和比表面积的微/纳米纤维膜的静电纺丝工艺。当不断/均匀地在靶材上沉积微/纳米纤维膜时，电纺纤维需要冲洗掉高电荷和过量的剩余溶剂，因为这些因素会中断电纺纤维在基材上的恒定沉积速度。直接电纺工艺可以克服这些限制，它可以通过引导电极的窗口和电纺纤维在吹风系统纺丝过程中的残留溶剂来降低电纺纤维的电荷。由于电纺纤维的电荷积累减少，微/纳米纤维可以沉积在任何类型的靶材上，靶材可以是导电材料或非导电材料。所制得的膜具有显著降低的电荷、残留溶剂浓度、足够的拉伸模数和较小的孔径分布。为了观察其作为生物医用创面敷料材料的可能性，对所制得的膜进行了细菌屏蔽试验。
An electrospinning process has been introduced to fabricate micro/nanofiber membranes having high porosity and specific surface area. When constantly/uniformly depositing the micro/nanofiber membrane on a target, the electrospun fibers require flushing out of the high charge and excessive remaining solvent built up, since these factors can interrupt the constant deposition rate of the electrospun fibers on substrates. These limitations can be overcome with a direct-electrospinning process, which can lower the charges of the electrospun fibers through a window of guiding electrodes and remaining solvent of the electrospun fibers during the spinning process by an air-blowing system. Because of the reduced charge accumulation of the electrospun fibers, the micro/nanofibers can be deposited on any kind of target, which may be a conductive or a non-conductive material. The fabricated membrane had a dramatically reduced charge, remaining solvent concentration, sufficient tensile modulus, and small pore-size distribution. To observe the possibility as a biomedical wound-dressing material, a bacteria-shielding test of the fabricated membrane was conducted.