Correlation between olfactory acuity and sinonasal radiological findings in adult patients with chronic rhinosinusitis.
Correlation between olfactory acuity and sinonasal radiological findings in adult patients with chronic rhinosinusitis.
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DOI：
10.1016/j.anl.2015.12.007
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发表时间：
2016-08
期刊：
影响因子：
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通讯作者：
Takahiro Saito;K. Tsuzuki;Yoriko Yukitatsu;M. Sakagami
中科院分区：
文献类型：
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作者：
Takahiro Saito;K. Tsuzuki;Yoriko Yukitatsu;M. Sakagami
目的探讨慢性鼻窦炎（CRS）患者嗅觉障碍严重程度与术前影像学表现的相关性。方法2007 - 2014年，272例双侧CRS嗅觉障碍患者（男性163例，女性109例，年龄22-80岁）计划行原发性内窥镜鼻窦手术（ESS）。研究两组：嗜酸性CRS (ECRS,n= 193)；非ecrs （n= 79）。采用T&T嗅觉仪识别和静脉嗅觉试验。应用计算机断层扫描（CT）对鼻窦和嗅裂（OC）进行评分。统计分析嗅觉敏锐度与CT评分的相关性。结果两组患者的识别阈值与CT评分有显著相关性。ECRS组的识别阈值和CT评分明显高于非ECRS组。CT评分与识别阈值的相关性最强。静脉嗅觉试验阳性患者（239例）的全窦和OC CT评分明显轻于阴性组（29例），但筛窦CT评分无明显差异。结论嗅觉障碍严重程度与CT混浊有显著相关性。ECRS患者的嗅觉障碍和CT表现比非ECRS患者更严重。
ObjectiveThis study aimed to clarify the correlation between olfactory disorder severity and radiological findings in patients with chronic rhinosinusitis (CRS) in the preoperative stage.MethodsFrom 2007 to 2014, 272 adult patients (163 men, 109 women; age range 22–80 years) with olfactory disorder due to bilateral CRS who were scheduled to undergo primary endoscopic sinus surgery (ESS) were enrolled. Two groups were studied: eosinophilic CRS (ECRS,n= 193); and non-ECRS (n= 79). T&T olfactometer recognition and intravenous olfaction tests were used. Computed tomography (CT) scores for sinuses and olfactory clefts (OC) were applied. Correlations between olfactory acuity and CT score were statistically analysed.ResultsIn both groups, recognition threshold correlated significantly with CT score. Recognition threshold and CT score were significantly more severe in ECRS than in non-ECRS. CT score at OC showed the strongest correlation with recognition threshold. CT scores for total sinuses and OC in patients showing a positive response to the intravenous olfaction test (239 patients) were significantly milder than those in the negative group (29 patients), but ethmoid CT score was not.ConclusionOlfactory disorder severity correlated significantly with CT opacification. Olfactory disorder and CT findings were more severe in patients with ECRS than in those with non-ECRS.