The challenge of pregnancy for patients with SLE

The challenge of pregnancy for patients with SLE
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DOI:
10.1177/0961203313504637
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发表时间:
2013-10-01
期刊:
影响因子:
2.6
通讯作者:
Khamashta, M. A.
Khamashta, M. A.
中科院分区:
医学4区
文献类型:
--
作者:
Ateka-Barrutia, O.;Khamashta, M. A.

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怀孕对照顾系统性红斑狼疮妇女的医生来说是一个重要的挑战。了解药物的安全性、怀孕对这类疾病的影响以及怀孕对这类疾病的影响,再加上多学科团队护理,是向这些妇女提供最佳产科和医疗护理所需的基本基石。受孕前咨询是一种理想的情况,可以总结病人以前的产科史、器官损伤、疾病活动、血清学特征和其他病史。在此阶段还应提出有关药物调整、计划的扫描和访视以及主要风险讨论的重要问题。计划怀孕对母亲和婴儿都有更好的结果。在整个怀孕和产褥期进行密切监测,并采取量身定制的管理方法,保证这些妇女的成功怀孕率最高。
Pregnancy poses an important challenge for doctors looking after women with systemic lupus erythematosus. Knowledge about safety of medications, the effect of pregnancy on such disease, and vice versa, together with multidisciplinary team care, are basic cornerstones needed to provide the best obstetric and medical care to these women. Pre-conceptional counselling constitutes the ideal scenario where a patient's previous obstetric history, organ damage, disease activity, serological profile and additional medical history can be summarized. Important issues regarding medication adjustment, planned scans and visits, and main risks discussion should also be raised at this stage. Planned pregnancies lead to better outcomes for both mothers and babies. Close surveillance throughout pregnancy and the puerperium, and tailored management approach guarantee the highest rates of successful pregnancies in these women.