Internalins: a complex family of leucine-rich repeat-containing proteins in Listeria monocytogenes

Internalins: a complex family of leucine-rich repeat-containing proteins in Listeria monocytogenes
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DOI:
10.1016/j.micinf.2007.05.003
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发表时间:
2007-08-01
影响因子:
5.8
通讯作者:
Cossart, R.
Cossart, R.
中科院分区:
医学3区
文献类型:
--
作者:
Bierne, H.;Sabet, C.;Cossart, R.

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单核细胞增多性李斯特菌基因组包括一个大家族的蛋白质,该蛋白质含有富含亮氨酸的重复序列,称为内化蛋白(Inl)。新突变体的产生和李斯特菌和其他细菌基因组中Inl变异性的比较分析表明,除了广泛研究的侵袭素InlA和InlB之外,另外的内化蛋白也在感染过程中发挥重要功能。(C)2007年,Elsevier Masson SAS。All rights reserved.
The Listeria monocytogenes genome includes a large family of proteins harbouring leucine-rich repeats known as internalins (Inl). The generation of novel mutants and comparative analysis of Inl variability among Listeria and other bacterial genomes suggest that beyond the extensively- studied invasins, InlA and InlB, additional internalins also play important functions in the infectious process. (C) 2007 Elsevier Masson SAS. All rights reserved.