ボウシュウボラの毒化機構-トゲモミジAstropecten polyacanthusにおけるテトロドトキシンの検出
ボウシュウボラの毒化機構-トゲモミジAstropecten polyacanthusにおけるテトロドトキシンの検出
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鲻鱼中毒机制——刺枫Astrofecten polyacanthus中河豚毒素的检测
DOI：
10.2331/suisan.48.1173
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发表时间：
1982
影响因子：
0.4
通讯作者：
周久 橋本
中科院分区：
文献类型：
--
作者：
玉雄 野口;弘子 成田;純一 丸山;周久 橋本
在研究河豚毒素（Tetrodotoxin，TTX）对“博舒波拉“（Boshubora）的消化道内容物中，经常发现多棘星栉海星（Astropecten polyacanthus）的某些部分。从有毒的博舒博拉标本采集地采集的该海星标本中检测到麻痹性毒性。尝试从海星中分离出负责的毒素，方法基本上与以前研究来自博舒博拉的TTX所用的方法相同。从部分纯化的毒素的薄层色谱和电泳结果，以及其TMS衍生物的GC-MS，很难区分与真实的TTX制剂，证明了两种毒素的同一性。因此，可以得出结论，在有毒的boshubora中积累的TTX来自这种海星，它已经被摄入。
During examination of the, mechanism involved in tetrodotoxin (TTX) -toxification of a trumpet shell, “ boshubora ” Charonia sauliae, parts of the starfish Astropecten polyacanthus were often found in the contents of the boshubora ' s digestive tract. Paralytic toxicty was detected in specimens of this starfish collected from the places where toxic boshubora specimens were taken. Attempts were made to isolate the responsible toxin from the starfish y essentially the same methods as used previously fro studying the TTX from boshubora. The thin-layer chronatographic and electrophoretic results from the partially purified toxin, and the GC-MS of its TMS-dericvative, were hardly distinguishable from those of the authentic preparation of TTX, demonstrating the identity of the two toxins. Thereflre, it was concluded that the TTX which accumulated in the toxic boshubora came from this starfish, which had been ingested.