Coupling reaction of alkyl chlorides with silyl enolates catalyzed by indium trihalide
Coupling reaction of alkyl chlorides with silyl enolates catalyzed by indium trihalide
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DOI：
10.1021/ol701684n
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发表时间：
2007-11-22
期刊：
影响因子：
5.2
通讯作者：
Baba, Akio
中科院分区：
文献类型：
--
作者：
Nishimoto, Yoshihiro;Yasuda, Makoto;Baba, Akio
卤化铟（III）不仅催化烷基氯化物与酯、酮和醛衍生的甲硅烷基烯醇化物的偶联，得到各种α-烷基化羰基化合物，而且还催化醛烯醇化物、烷基氯化物和烯丙基硅烷或炔基硅烷的一锅三组分反应。
Indium(III) halide catalyzed not only the coupling of alkyl chlorides with silyl enolates derived from esters, ketones, and aldehydes to give a variety of alpha-alkylated carbonyl compounds but also one-pot, three-component reactions of aldehyde enolate, alkyl chloride, and allylsilane or alkynylsilane.