Functional reorganization in thalamocortical networks: transition between spindling and delta sleep rhythms.

Functional reorganization in thalamocortical networks: transition between spindling and delta sleep rhythms.
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丘脑皮质网络的功能重组:纺锤形睡眠节律和三角洲睡眠节律之间的过渡。

DOI:
10.1073/pnas.93.26.15417
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发表时间:
1996
影响因子:
11.1
通讯作者:
Kopell,N
Kopell,N
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Terman,D;Bose,A;Kopell,N

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Thalamic reticularis, thalamocortical, and cortical cells participate in the 7–14-hz spindling rhythm of early sleep and the slower delta rhythms of deeper sleep, with different firing patterns. In this case study, showing the interactions of intrinsic and synaptic properties, a change in the conductance of one kind of cell effectively rewires the thalamocortical circuit, leading to the transition from the spindling to the delta rhythm. The two rhythms make different uses of the fast (GABAA) and slow (GABAB) inhibition generated by the thalamic reticularis cells.