Mortality and Resource Use Following Cardiac Interventions in Children with Trisomy 13 and Trisomy 18 and Congenital Heart Disease
Mortality and Resource Use Following Cardiac Interventions in Children with Trisomy 13 and Trisomy 18 and Congenital Heart Disease
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DOI：
10.1007/s00246-018-2001-x
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发表时间：
2019-02-01
影响因子：
1.6
通讯作者：
Menon, Shaji C.
中科院分区：
文献类型：
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作者：
Domingo, Liezl;Carey, John C.;Menon, Shaji C.
我们试图评估13三体（T13）和18三体（T18）儿童心脏介入治疗后的死亡率、死亡风险因素和资源利用。1999年1月至2015年3月接受心脏介入治疗的所有T13和T18儿童均来自儿科健康信息系统数据库。收集的数据包括人口统计学、先天性心脏病（CHD）类型、心脏介入、合并症、住院时间（LOS）、住院费用和死亡（30天内）。Logistic回归分析用于确定与死亡率相关的因素。有49例（47%女性）T13和140例（67%女性）T18受试者。这两个群体在种族、地理区域、保险类型和家庭收入中位数方面的分布相似。两组中最常见的CHD是分流病变，其次是圆锥动脉干缺陷。与T18相比，T13队列的死亡率（29% vs. 12%）、气管造口（12% vs. 4%）、胃造口（18% vs. 6%）和总体资源使用（P
We sought to evaluate the mortality, risk factors for mortality, and resource utilization following cardiac interventions in trisomy 13 (T13) and 18 (T18) children. All T13 and T18 children who underwent a cardiac intervention from January 1999 to March 2015 were identified from the Pediatric Health Information System database. Data collected included demographics, type of congenital heart disease (CHD), cardiac interventions, comorbidities, length of stay (LOS), hospital charges, and deaths (within 30 days). Logistic regression analysis was used to determine factors associated with mortality. There were 49 (47% females) T13 and 140 (67% females) T18 subjects. The two cohorts were similar in distribution for race, geographic region, insurance type, and median household income. The most common CHD in both groups was a shunt lesion followed by conotruncal defects. Compared to T18, the T13 cohort had higher mortality (29% vs. 12%), tracheostomies (12% vs. 4%), gastrostomies (18% vs. 6%), and overall resource use (P