Concise, regioselective synthesis of the ABC tristetrahydropyran of thyrsiferol and venustatriol.
Concise, regioselective synthesis of the ABC tristetrahydropyran of thyrsiferol and venustatriol.
复制标题
thyrsiferol 和 venustatriol 的 ABC 三四氢吡喃的简洁区域选择性合成。
作者：
F. McDonald;Xudong Wei
[结构：见正文] 天然产物 thyrsiferol (2) 和 venustatriol (3) 的 ABC 三四氢吡喃子结构 1 由乙酸法呢酯经过 14 个步骤合成，有效控制了每个四氢吡喃环形成过程中区域和立体选择性的各个方面。
[structure: see text] The ABC tristetrahydropyran substructure 1 of the natural products thyrsiferol (2) and venustatriol (3) has been synthesized in 14 steps from farnesyl acetate, with effective control of all aspects of regio- and stereoselectivity in the formation of each tetrahydropyran ring.