The effects of age on kinetics of oxygen uptake and phosphocreatine in humans during exercise
The effects of age on kinetics of oxygen uptake and phosphocreatine in humans during exercise
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DOI：
10.1113/expphysiol.1998.sp004087
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发表时间：
1998-01-01
影响因子：
2.7
通讯作者：
Thompson, RT
中科院分区：
文献类型：
--
作者：
Chilibeck, PD;Paterson, DH;Thompson, RT
We compared the kinetics of oxygen uptake (Vover dot(O2)) and phosphocreatine (PCr) during the adjustment to and recovery from plantar flexion exercise In moderately active older (n = 10, 66.9 years) and younger (n = 10, 27.5 years) individuals. Vover dot(O2) kinetics were similar in the two groups, with time constants (tau) averaging 46.3 +/- 10.2 s (younger, on-transient), 38.1 +/- 14.4 s (younger, off-transient), 46.3 +/- 17.8 (older, on-transient) and 40.7 +/- 19.2 s (older, off-transient). These were similar to corresponding PCr kinetics, measured by P-31 nuclear magnetic resonance spectroscopy, which averaged 50.6 +/- 24.0 s (younger, on-transient), 42.0 +/- 16.1 s (younger, off-transient), 39.8 +/- 22.0 s (older, on-transient) and 37.6 +/- 21.6 s (older, off-transient). On-transient tau values for Vover dot(O2) and PCr were correlated, for combined groups (r = 0 53; P = 0.015). We conclude that: (1) Vover dot(O2) and PCr kinetics during exercise of a muscle group accustomed to daily activity are not compromised in physically active older humans, and (2) PCr kinetics reflect the kinetics of muscle O-2 consumption, and are expressed at the lung (Vover dot(O2) kinetics) after a transit delay.
