PLASMA PANCREATIC POLYPEPTIDE IN THE HUMAN NEONATE
PLASMA PANCREATIC POLYPEPTIDE IN THE HUMAN NEONATE
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人类新生儿血浆胰腺多肽
DOI：
10.1111/j.1651-2227.1980.tb07062.x
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发表时间：
1980
期刊：
影响因子：
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通讯作者：
A. Aynsley
中科院分区：
文献类型：
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作者：
A. Lucas;T. Adrian;S. R. Bloom;A. Aynsley
抽象的。卢卡斯，A.，Adrian，T. E、Bloom，S. R. Aynsley绿色，A.（牛津大学儿科系，约翰拉德克利夫医院和伦敦哈默史密斯医院）。人新生儿血浆胰多肽。Acta Paediatr Scand，69：211，1980.-对197例健康足月儿和早产儿血浆胰多肽（PP）浓度进行了研究。出生时血浆浓度低于禁食的年轻成人（p > 0.01），但到出生后第6天，足月儿和早产儿的基础浓度已升至成人水平。在出生后13天和24天的早产儿中，基础血浆PP浓度在出生后13天达到峰值，其水平是禁食成人的两倍多（p > 0.005）。然而，在研究的任何新生儿组中均未观察到在成人中报告的喂养后PP显著升高。因此，新生儿和成人的PP生理学似乎不同。这些发现可能与适应产后生活有关。
Abstract. Lucas, A., Adrian, T. E., Bloom, S. R. and Aynsley‐Green, A. (University Department of Paediatrics, John Radcliffe Hospital, Oxford and Hammersmith Hospital, London). Plasma pancreatic polypeptide in the human neonate. Acta Paediatr Scand, 69: 211, 1980.—Plasma pancreatic polypeptide (PP) concentrations have been studied in 197 healthy term and preterm infants. At birth plasma concentrations were lower than those found in the young fasting adult (p > 0.01), but by the sixth postnatal day in both term and preterm infants basal concentrations had risen to adult levels. In preterm infants, who were studied at two further postnatal ages, 13 and 24 days, basal plasma PP concentrations peaked at 13 days with levels that were over twice those seen in fasting adults (p > 0.005). However, the marked PP elevations following feeding that have been reported in adults, were not seen in any of the groups of neonates studied. PP physiology thus appears to differ in neonates and adults. These findings may be relevant to adaptation to postnatal life.