Disentangling Syntax and Intelligibility in Auditory Language Comprehension
Disentangling Syntax and Intelligibility in Auditory Language Comprehension
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DOI：
10.1002/hbm.20878
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发表时间：
2010-03-01
影响因子：
4.8
通讯作者：
Obleser, Jonas
中科院分区：
文献类型：
--
作者：
Friederici, Angela D.;Kotz, Sonja A.;Obleser, Jonas
对口语理解的神经基础的研究通常集中在不同信号可理解性的听觉处理方面，或语言处理的更高层次方面，如语法。这两种语言研究的大多数研究都报告了大脑的激活，包括颞上回（STG）和/或颞上沟（STS）的峰值，但尚不清楚为什么这些区域在功能不同的研究中被招募。当前的fMRI研究旨在在正交设计中解开可理解性和语法的功能神经解剖学。这些数据证实了左右半球STS和STG之间的功能分离：首先，言语可理解性操纵导致双侧STG中前峰激活，而句法短语结构违规则导致强烈的左偏侧STG中前峰和后峰激活。其次，ROI分析表明，语音可理解性和句法正确性的所有相互作用都位于左额叶皮层和颞叶皮层，而观察到的右半球激活反映了对可理解性和句法的不太具体的反应。我们的数据表明，中前侧STS激活与语音清晰度的提高有关，而中后侧STG/STS对语音中的句法信息更为敏感。中国生物医学工程学报（英文版），2010。(C) 2009 Wiley-Liss, Inc。
Studies of the neural basis of spoken language comprehension typically focus on aspects of auditory processing by varying signal intelligibility, or on higher-level aspects of language processing such as syntax. Most studies in either of these threads of language research report brain activation including peaks in the superior temporal gyrus (STG) and/or the superior temporal sulcus (STS), but it is not clear why these areas are recruited in functionally different studies. The current fMRI study aims to disentangle the functional neuroanatomy of intelligibility and syntax in an orthogonal design. The data substantiate functional dissociations between STS and STG in the left and right hemispheres: first, manipulations of speech intelligibility yield bilateral mid-anterior STS peak activation, whereas syntactic phrase structure violations elicit strongly left-lateralized mid STG and posterior STS activation. Second, ROI analyses indicate all interactions of speech intelligibility and syntactic correctness to be located in the left frontal and temporal cortex, while the observed right-hemispheric activations reflect less specific responses to intelligibility and syntax. Our data demonstrate that the mid-to-anterior STS activation is associated with increasing speech intelligibility, while the mid-to-posterior STG/STS is more sensitive to syntactic information within the speech. Hum Brain Mapp 31:448-457, 2010. (C) 2009 Wiley-Liss, Inc.