Adherence to the 2006 American Heart Association Diet and Lifestyle Recommendations for cardiovascular disease risk reduction is associated with bone health in older Puerto Ricans
Adherence to the 2006 American Heart Association Diet and Lifestyle Recommendations for cardiovascular disease risk reduction is associated with bone health in older Puerto Ricans
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DOI：
10.3945/ajcn.112.056267
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发表时间：
2013-11-01
影响因子：
7.1
通讯作者：
Tucker, Katherine L.
中科院分区：
文献类型：
--
作者：
Bhupathiraju, Shilpa N.;Lichtenstein, Alice H.;Tucker, Katherine L.
背景：心血管疾病（CVD）和骨质疏松症是具有共同病理生理机制的两大公共卫生问题。降低 CVD 风险的策略也可能有益于骨骼健康。目的：我们测试了遵守 2006 年美国心脏协会饮食和生活方式建议 (AHA-DLR) 与骨骼健康相关的假设。设计：我们之前开发了独特的饮食和生活方式评分（美国心脏协会饮食和生活方式评分；AHA-DLS）来评估对 AHA-DLR 的遵守情况。在一项针对 933 名 47-79 岁波多黎各人的横断面研究中，我们修改了 AHA-DLS 以测试与骨骼健康的关联。使用双能 X 射线吸收仪测量股骨颈、转子、全髋和腰椎 (L2-L4) 处的骨密度 (BMD)。结果：改良 AHA-DLS 每增加 5 个单位，股骨颈、转子、全髋和腰椎 (L2-L4) 处的 BMD 与0.005-0.008-g/cm(2) (P < 0.05) 较高值。 AHA-DLR 中没有任何成分单独导致观察到的正相关。改良 AHA-DLS 每增加 5 个单位，转子、全髋和腰椎 (L2-L4) 发生骨质疏松或骨质减少的几率就会降低 14%（OR：0.86；95% CI：0.79，0.92）、17%（OR：0.83；95% CI：0.76、0.92）和分别为 9%（OR：0.91；95% CI：0.84、0.99）。结论：降低 CVD 风险的膳食指南也可能有利于该西班牙裔人群的骨骼健康。同步这两种常见疾病的饮食指南可能会提供简化的公共卫生信息。
Background: Cardiovascular disease (CVD) and osteoporosis are 2 major public health problems that share common pathophysiological mechanisms. It is possible that strategies to reduce CVD risk may also benefit bone health.Objective: We tested the hypothesis that adherence to the 2006 American Heart Association Diet and Lifestyle Recommendations (AHA-DLR) is associated with bone health.Design: We previously developed a unique diet and lifestyle score (American Heart Association Diet and Lifestyle Score; AHA-DLS) to assess adherence to the AHA-DLR. In a cross-sectional study of 933 Puerto Ricans aged 47-79 y, we modified the AHA-DLS to test associations with bone health. Bone mineral density (BMD) at the femoral neck, trochanter, total hip, and lumbar spine (L2-L4) was measured by using dual-energy X-ray absorptiometry.Results: For every 5-unit increase in the modified AHA-DLS, BMD at the femoral neck, trochanter, total hip, and lumbar spine (L2-L4) was associated with a 0.005-0.008-g/cm(2) (P < 0.05) higher value. No component of the AHA-DLR alone was responsible for the observed positive associations. For every 5-unit increase in the modified AHA-DLS, the odds for osteoporosis or osteopenia at the trochanter, total hip, and lumbar spine (L2-L4) were lower by 14% (OR: 0.86; 95% CI: 0.79, 0.92), 17% (OR: 0.83; 95% CI: 0.76, 0.92), and 9% (OR: 0.91; 95% CI: 0.84, 0.99), respectively.Conclusions: Dietary guidelines for CVD risk reduction may also benefit bone health in this Hispanic cohort. Synchronizing dietary guidelines for these 2 common diseases may provide a simplified public health message.