Responsiveness and minimally important change for the Manchester-Oxford foot questionnaire (MOXFQ) compared with AOFAS and SF-36 assessments following surgery for hallux valgus
Responsiveness and minimally important change for the Manchester-Oxford foot questionnaire (MOXFQ) compared with AOFAS and SF-36 assessments following surgery for hallux valgus
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DOI：
10.1016/j.joca.2007.02.003
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发表时间：
2007-08-01
影响因子：
7
通讯作者：
Jenkinson, C.
中科院分区：
文献类型：
--
作者：
Dawson, J.;Doll, H.;Jenkinson, C.
目的：使用锚定和基于分布的方法评估曼彻斯特-牛津足部问卷(MOXFQ)的响应性和最小重要变化(MIC)。将反应性、最小临床重要差异(MCID)和最小可检测变化的估计与简表36(SF-36)和美国矫形外科足踝协会(AOFAS)的测量结果进行比较。方法：对91名在骨科医院接受拇外翻手术的患者(125足手术)进行前瞻性观察研究。在手术前和术后12个月，患者完成MOXFQ和SF-36，足外科医生评估对应于足部四个区域的所有四个AOFAS评分。结果：每种工具各领域的平均变化均有统计学意义，但足部特定的MOXFQ和AOFAS领域产生的效应大小(>；1)远大于任何SF-36领域，显示出更好的响应性。过渡项目与所有MOXFQ和AOFAS得分之间存在明显的相关性，但只与SF-36的一个(身体功能)领域相关。基于锚定和分布的方法确定了MIC的一般可比测量，对于MOXFQ和AOFAS域，其测量标准误差在1到2之间。MOXFQ行走/站立、疼痛和社会互动领域的MCID分别为16、12和24。结论：对于拇外翻手术，MOXFQ具有高度的响应性。性能与AOFAS相当，明显好于通用SF-36。MOXFQ的最低抑菌浓度的研究估计对于未来临床试验的样本量计算是有用的。(C)2007年国际骨性关节炎研究会。爱思唯尔有限公司出版。保留所有权利。
Objectives: To assess responsiveness and minimally important change (MIC) for the Manchester-Oxford foot questionnaire (MOXFQ) using anchor and distribution-based approaches. Responsiveness and estimates of minimal clinically important difference (MCID) and minimal detectable change are compared with those from the Short-Form 36 (SF-36) and American Orthopaedic Foot & Ankle Society (AOFAS) measures.Methods: A prospective observational study of 91 consecutive patients (125 foot operations) undergoing hallux valgus surgery at an orthopaedic hospital. Pre- and 12 month post-surgery, patients completed the MOXFQ and SF-36 and foot surgeons assessed all four AOFAS scores corresponding to four regions of the foot. Transition items were asked about perceived changes compared with before surgery.Results: Mean changes in all domains of each instrument were statistically significant, but foot-specific MOXFQ and AOFAS domains produced much larger effect sizes (>1) than any SF-36 domains, indicating superior responsiveness. Clear associations occurred between transition items and all MOXFQ and AOFAS scores, but with only one (physical function) SF-36 domain. Anchor and distribution-based approaches identified generally comparable measures of MIC, which for the MOXFQ and AOFAS domains were between 1 and 2 standard error of measurement. In metric terms, the MCIDs were 16, 12, and 24 for the MOXFQ Walking/standing, Pain, and Social Interaction domains, respectively.Conclusions: For hallux valgus surgery, the MOXFQ is highly responsive. Performance is comparable to the AOFAS and notably better than the generic SF-36. Study estimates of MIC for the MOXFQ are useful to inform sample-size calculations for future clinical trials. (c) 2007 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.