Radiofrequency ablation of chondroblastoma: procedure technique, clinical and MR imaging follow up of four cases
Radiofrequency ablation of chondroblastoma: procedure technique, clinical and MR imaging follow up of four cases
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DOI：
10.1007/s00256-008-0526-4
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发表时间：
2008-11-01
影响因子：
2.1
通讯作者：
James, S. L. J.
中科院分区：
文献类型：
--
作者：
Christie-Large, M.;Evans, N.;James, S. L. J.
目的本研究的目的是描述射频消融治疗成软骨细胞瘤患者的手术技术，临床和影像学结果。材料与方法4例患者行手术治疗，男女比例3:1，平均年龄13岁，年龄范围9 ~ 16岁。所有患者术前都有磁共振成像（MRI）和有症状的，活检证实的成软骨细胞瘤（两个股骨近端，两个胫骨近端）。病变最大尺寸为1.5 ~ 2.5 cm，平均尺寸为1.8 cm。通过Bonopty活检针系统获得骨通路（平均射频针放置次数5次；平均消融时间31分钟）。结果所有病例均获得临床及MRI随访（平均12.25个月，范围5-18个月）。所有患者均报告消融后2-6周症状缓解。在最近的临床随访中，三名患者完全无症状，完全恢复正常活动，一名患者有轻微的局部不适（不同的疼痛模式），但没有限制活动。所有4例患者的随访MRI研究均显示病变周围水肿模式的消退以及脂肪替代后内部信号特征的时间演变。结论射频消融术治疗成软骨细胞瘤提供了一种手术刮除的替代方法，我们已经证明了临床症状和后续MRI表现的改善。
Purpose The aim of this study is to describe the procedure technique, clinical and imaging outcomes of patients treated with radiofrequency ablation for chondroblastoma.Materials and methods Four patients (female/male, 3:1; mean age, 13 years; age range; 9-16 years) underwent the procedure. All had pre-operative magnetic resonance imaging (MRI) and symptomatic, biopsy-proven chondroblastomas (two proximal femur, two proximal tibia). The lesion size ranged from 1.5 to 2.5 cm in maximal dimension (mean size, 1.8 cm). Bone access was gained with a Bonopty biopsy needle system (mean number of radiofrequency needle placements, 5; mean ablation time, 31 min).Results Clinical and MRI follow-up was available in all cases (mean, 12.25 months; range, 5-18 months). All patients reported resolution of symptoms at 2-6 weeks post ablation. At their most recent clinical follow-up, three patients remained completely asymptomatic with full return to normal activities and one patient had minor local discomfort (different pain pattern) that was not limiting activity. All four patients' follow-up MRI studies demonstrated resolution of the oedema pattern around the lesion and temporal evolution of the internal signal characteristics with fatty replacement.Conclusion Radiofrequency ablation for chondroblastoma provides an alternative to surgical curettage, and we have demonstrated both a clinical improvement in symptoms and the follow-up MRI appearances.