The Search for an Efficient Black Fly Trap for Xenomonitoring of Onchocerciasis.
The Search for an Efficient Black Fly Trap for Xenomonitoring of Onchocerciasis.
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DOI：
10.1155/2018/5902367
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发表时间：
2018
影响因子：
2.2
通讯作者：
Unnasch TR
中科院分区：
文献类型：
--
作者：
Otabil KB;Gyasi SF;Awuah E;Obeng-Ofori D;Rodríguez-Pérez MA;Katholi CR;Unnasch TR
盘尾丝虫病是一种被忽视的热带疾病，几十年来一直困扰着人类，其病理涉及眼睛和皮肤。世界卫生组织和全球卫生界已指定到2045年在全球消灭这种疾病。然而，随着控制规划的重点从减轻疾病负担转向消除疾病，可能需要新的工具和战略来实现具体目标。在黑蝇媒介中监测盘尾丝虫幼虫是监测疾病动态和确认消灭的重要工具。几十年来，人类登陆采集一直是获取病媒以监测该疾病的唯一手段。这一过程一直受到伦理问题的困扰，有时无法捕获足够的黑蝇来进行有效的监测。自20世纪60年代以来，世界卫生组织认识到需要取代人类着陆收集，但相对较少的实地研究设计和测试了替代陷阱。这篇综述文章系统地讨论了一些测试过的关键陷阱、它们的成功之处以及它们面临的挑战。审查的目的是将研究和开发重点放在最成功和最有前途的媒介陷阱上，这些陷阱可能取代人类着陆收集。
Onchocerciasis is a neglected tropical disease that has plagued mankind for decades with pathologies that involve the eyes and the skin. The WHO and the global health community have earmarked the disease for global elimination by 2045. However, as control programmes shift focus from reduction of the burden of the disease to elimination, new tools and strategies may be needed to meet targets. Monitoring Onchocerca volvulus larvae in the black fly vectors is an important tool needed to monitor disease dynamics and certify elimination. For decades, human landing collections have been the sole means of acquiring vectors for monitoring of the disease. This procedure has been plagued with ethical concerns and sometimes the inability to harvest enough black flies needed to carry out effective monitoring. Since the 1960s, the WHO recognized the need to replace human landing collections but relatively few field studies have designed and tested alternative traps. This review article systematically discusses some of the key traps tested, their successes, and their challenges. It is the aim of the review to direct research and development focus to the most successful and promising vector traps which could potentially replace the human landing collections.