Critical appraisal of the 2020 ESC guideline recommendations on diagnosis and risk assessment in patients with suspected non-ST-segment elevation acute coronary syndrome.

Critical appraisal of the 2020 ESC guideline recommendations on diagnosis and risk assessment in patients with suspected non-ST-segment elevation acute coronary syndrome.
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DOI:
10.1007/s00392-021-01821-2
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发表时间:
2021-09
期刊:
Clinical research in cardiology : official journal of the German Cardiac Society
影响因子:
--
通讯作者:
Huber K
Huber K
中科院分区:
其他
文献类型:
--
作者:
Giannitsis E;Blankenberg S;Christenson RH;Frey N;von Haehling S;Hamm CW;Inoue K;Katus HA;Lee CC;McCord J;Möckel M;Chieh JTW;Tubaro M;Wollert KC;Huber K

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2020年ESC指南中引入了多项新建议,用于急性冠状动脉综合征的管理,重点关注诊断、预后和无持续ST段抬高患者的管理。大多数建议都得到了高质量科学证据的支持。该指南提供了解决方案,以克服可能使肌钙蛋白结果的方便解释复杂化的障碍,例如年龄或性别特异性临界值,并提供实用建议以克服实验室报告的延迟。然而,在某些领域,科学支持没有得到很好的记录,甚至没有,而其他领域则是由专家意见或主观建议所涵盖。我们的目标是对主要与诊断和预后评估相关的几项建议进行批判性评价,强调指南建议与现有科学证据之间的差异。
Multiple new recommendations have been introduced in the 2020 ESC guidelines for the management of acute coronary syndromes with a focus on diagnosis, prognosis, and management of patients presenting without persistent ST-segment elevation. Most recommendations are supported by high-quality scientific evidence. The guidelines provide solutions to overcome obstacles presumed to complicate a convenient interpretation of troponin results such as age-, or sex-specific cutoffs, and to give practical advice to overcome delays of laboratory reporting. However, in some areas, scientific support is less well documented or even missing, and other areas are covered rather by expert opinion or subjective recommendations. We aim to provide a critical appraisal on several recommendations, mainly related to the diagnostic and prognostic assessment, highlighting the discrepancies between Guideline recommendations and the existing scientific evidence.
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