TOTAL PINEALECTOMY BY AN OCCIPITAL PARASAGITTAL APPROACH IN SHEEP
TOTAL PINEALECTOMY BY AN OCCIPITAL PARASAGITTAL APPROACH IN SHEEP
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DOI：
10.1016/0090-3019(82)90157-4
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发表时间：
1982-01-01
影响因子：
--
通讯作者：
KINDT, GW
中科院分区：
文献类型：
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作者：
DEMPSEY, RJ;HOPKINS, J;KINDT, GW
一种可靠的方法，全松果体切除术在羊没有导致显着的神经功能缺损的发展和描述。已知的光对绵羊促性腺激素水平的影响有助于验证其松果体的这些研究。特别注意的是描绘的外科解剖的腺体和它的关系下放大中央引流静脉的大脑。在这种大型哺乳动物中，这种关系与人类有很大不同。使用放大镜进行半球内枕骨暴露，以及术前给予类固醇和渗透剂，有助于最大限度地减少牵拉和脑水肿的影响。松果体切除术的成功率增加到83%，允许适合研究松果体和垂体的神经内分泌功能的动物群的发展。
A reliable method of total pinealectomy in sheep without a resulting significant neurological deficit was developed and described. The known effect of light on sheep gonadotropin levels helps validate these studies of its pineal gland. Special attention is given to delineation of the surgical anatomy of the gland and its relationship under magnification to the central draining veins of the brain. In this large mammal this relationship differs considerably from that of humans. The application of an intrahemispheric occipital exposure using magnification, as well as the preoperative administration of steroids and osmotic agents, helped to minimize the effects of retraction and resultant cerebral edema. The rate of successful pinealectomy was increased to 83%, allowing the development of groups of animals suitable for studies of the neuroendocrine function of the pineal and pituitary glands.