Uricaemia and ejection fraction in elderly heart failure outpatients

Uricaemia and ejection fraction in elderly heart failure outpatients
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DOI:
10.1111/eci.12273
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发表时间:
2014-06-01
影响因子:
5.5
通讯作者:
Cicero, Arrigo F. G.
Cicero, Arrigo F. G.
中科院分区:
医学3区
文献类型:
--
作者:
Borghi, Claudio;Cosentino, Eugenio R.;Cicero, Arrigo F. G.

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研究背景:初步资料表明,血尿酸(SUA)可能与慢性心力衰竭(HF)的预后有关。本研究的目的是在一组老年高血压门诊患者中检测SUA与左心室射血分数(EF%)的关系。设计我们连续入选了487例老年门诊患者(男=59.8%;女=40.2%;平均年龄:72 ± 11岁),评估SUA与EF%之间的关系。结果单因素分析显示,SUA与EF%呈负相关:B=-4.392,95% CI -5.427 ~-3.357,P
Background Preliminary data suggest that serum uric acid (SUA) could be involved in the prognosis of chronic heart failure (HF). The aim of our study was to test the relationship between SUA and left ventricular ejection fraction (EF%) in a cohort of elderly hypertensive outpatients with chronic HF.Design We consecutively enrolled 487 elderly outpatients (M=59.8%; F=40.2%; mean age: 72 +/- 11years old) affected by mild-to-moderate hypertensive and/or ischaemic HF, evaluating the relationship between SUA and EF%.Results In an univariate analysis, SUA was inversely related with EF%: B= -4.392, 95% CI -5.427 to -3.357, P