Neuroimaging in psychiatry: from bench to bedside

Neuroimaging in psychiatry: from bench to bedside
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DOI:
10.3389/neuro.09.049.2009
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发表时间:
2009-12-01
影响因子:
2.9
通讯作者:
Fallgatter, Andreas J.
Fallgatter, Andreas J.
中科院分区:
医学3区
文献类型:
--
作者:
Linden, David E. J.;Fallgatter, Andreas J.

文献摘要

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这一观点考虑了不同神经影像技术在精神病学领域当前和未来的作用。在确定了现代精神病学中主要以症状为中心的诊断过程和治疗决策的缺点后,我们提出了神经影像学方法有可能提供帮助的主题。这些包括更好地了解病理生理学、改进诊断、协助治疗决策以及通过直接评估与疾病相关的大脑功能的改善来监督治疗成功。这些不同的问题通过神经影像学研究的例子来说明,重点关注精神分裂症和抑郁症等严重的精神和神经精神疾病。尽管文章中提出了所有保留意见,但我们乐观地认为神经影像学在上述问题上具有巨大的潜力。我们预计神经影像学将在未来诊断过程的完善中发挥越来越重要的作用,并有助于精神病学领域新疗法的开发。
This perspective considers the present and the future role of different neuroimaging techniques in the field of psychiatry. After identifying shortcomings of the mainly symptom-focussed diagnostic processes and treatment decisions in modern psychiatry, we suggest topics where neuroimaging methods have the potential to help. These include better understanding of the pathophysiology, improved diagnoses, assistance in therapeutic decisions and the supervision of treatment success by direct assessment of improvement in disease-related brain functions. These different questions are illustrated by examples from neuroimaging studies, with a focus on severe mental and neuropsychiatric illnesses such as schizophrenia and depression. Despite all reservations addressed in the article, we are optimistic that neuroimaging has a huge potential with regard to the above-mentioned questions. We expect that neuroimaging will play an increasing role in the future refinement of the diagnostic process and aid in the development of new therapies in the field of psychiatry.