Diagnostic Accuracy of Seven Commercial Assays for Rapid Detection of Group A Rotavirus Antigens

Diagnostic Accuracy of Seven Commercial Assays for Rapid Detection of Group A Rotavirus Antigens
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七种快速检测 A 组轮状病毒抗原的商业化验方法的诊断准确性

DOI:
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发表时间:
2015
影响因子:
9.4
通讯作者:
P. Pothier
P. Pothier
中科院分区:
医学2区
文献类型:
--
作者:
J. Kaplon;C. Fremy;S. Pillet;Lucile Mendes Martins;K. Ambert‐Balay;S. Aho;P. Pothier

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摘要 对七种用于检测人类粪便样本中 A 组轮状病毒抗原的商业免疫层析测定进行了评估。这些检测显示出相似水平的诊断准确性,适用于检测急性胃肠炎患者的轮状病毒,但漏掉了一些通过实时逆转录 PCR 检测到的无症状轮状病毒脱落情况。
ABSTRACT Seven commercial immunochromatographic assays intended for the detection of group A rotavirus antigens in human stool samples were evaluated. These assays showed similar levels of diagnostic accuracy and were suitable for the detection of rotavirus in patients with acute gastroenteritis but missed some asymptomatic rotavirus shedding identified by real-time reverse transcription-PCR.